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Journal articleBrose U, Hirt MR, Ryser R, et al., 2025,
Embedding information flows within ecological networks
, NATURE ECOLOGY & EVOLUTION, Vol: 9, Pages: 547-558, ISSN: 2397-334X- Cite
- Citations: 3
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Journal articleWilliams B, Balvanera SM, Sethi SS, et al., 2025,
Unlocking the soundscape of coral reefs with artificial intelligence: pretrained networks and unsupervised learning win out
, PLOS COMPUTATIONAL BIOLOGY, Vol: 21, ISSN: 1553-734X- Cite
- Citations: 2
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Journal articleKientega M, Morianou I, Traore N, et al., 2025,
Genomic analyses revealed low genetic variation In the Intron-exon boundary of the <i>doublesex</i> gene within the natural populations of <i>An. gambiae</i> s.l. in Burkina Faso (vol 25, 1207, 2024)
, BMC GENOMICS, Vol: 26, ISSN: 1471-2164 -
Journal articleMansfield C, 2025,
‘We have learning objectives, not enjoyment objectives': the role of enjoyment in Life Sciences teaching and learning
, Journal of Learning Development in Higher Education<jats:p>Positive emotions such as enjoyment are often overlooked in higher education (HE) despite being important and prioritised in school-level policy. Enjoyment has been reported to have a positive impact on multiple aspects of learning – it can facilitate deep-learning strategies, boost confidence and encourage long-term interest. Many educators recognise the value of positive emotions in everyday life and for wellbeing. In addition, staff enjoyment of teaching is often overlooked in favour of a student-only perspective that may limit a holistic understanding of emotion in HE, given strong links between staff and student emotion and empathy. In the current HE climate, where students face huge pressure to achieve, and staff workloads are increasing, a focus on enjoyment could bring substantial benefits.This study provides a STEM-specific context and focuses on staff and student enjoyment of teaching and learning at a research-intensive university. Through interviews with teaching staff and Life Sciences students, this study explores what contributes to staff and student enjoyment of teaching and learning. Commonalities between staff and student enjoyment were identified and include the importance of relational pedagogy and positive relationships, as well as the freedom to be creative and explore a subject. Both themes have implications for learning development and teaching practice, including more intentional design of groupwork and small group teaching, and level of choice around topics and pedagogic approaches within programmes. Recommendations from this study include working towards relational and ‘emotionally literate’ pedagogy with potential implications for education practitioners and students in STEM and across HE.</jats:p>
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Journal articleSaunders T, Adkins J, Atwood TB, et al., 2025,
Goose herbivory effects on early-stage litter decomposition in coastal Alaskan wetlands
, PLANT AND SOIL, ISSN: 0032-079X -
Journal articleSayol F, Reijenga BR, Tobias JA, et al., 2025,
Ecophysical constraints on avian adaptation and diversification
, Current Biology, Vol: 35, Pages: 1326-1336.e6, ISSN: 0960-9822The evolution of morphological diversity is ultimately governed by physical laws and ecological contexts, which together impose a range of ecophysical constraints. Substantial progress has been made in identifying how these constraints shape the form and function of producers (plants), but similar knowledge is lacking for consumers, in part because the requisite data have not been available at sufficient scale for animals. Using morphometric measurements for all birds, we demonstrate that observed variation is restricted—both for beak shape and body shape—to triangular regions of morphospace with clearly defined boundaries and vertices (corners). By combining morphometric data with information on ecological and behavioral functions, we provide evidence that the extent of avian morphospace reflects a trade-off between three fundamental physical tasks for feeding (crush, engulf, and reach) that characterize resource acquisition and processing by the beak and three physical tasks (fly, swim, and walk) that characterize avian lifestyles or locomotion. Phylogenetic analyses suggest that trajectories of morphological evolution trend toward the vertices, with lineages evolving from a core of functional generalists toward more specialized physical tasks. We further propose that expansion beyond the current boundaries of morphospace is constrained by the shorter evolutionary lifespan of functional specialists, although patterns of speciation rate and current extinction risk provide only weak support for this hypothesis. Overall, we show that the structure of avian morphospace follows relatively simple rules defined by ecophysical constraints and trade-offs, shedding light on the processes shaping modern animal diversity and responses to environmental change.
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Journal articleWorsley MZ, Schroeder J, Dixit T, 2025,
How animals discriminate between stimulus magnitudes: a meta-analysis
, BEHAVIORAL ECOLOGY, Vol: 36, ISSN: 1045-2249 -
Journal articleBeeby M, Daum B, 2025,
How Does the Archaellum Work?
, BIOMOLECULES, Vol: 15 -
OtherChen S-YS, Marchal O, Andres M, et al., 2025,
Deep Cyclones in the western North Atlantic: Insight from a Regional Numerical Model with High Vertical Resolution
<jats:p>Deep cyclones (DCs) were observed in the western North Atlantic under meander troughs of the Gulf Stream (GS) west of the New England seamounts during the Synoptic Ocean Prediction (SYNOP) field campaign. Although subsequent dedicated observations have been sparse, DCs appear common underneath major surface-intensified western boundary current extensions. Recent model studies with idealised domains suggest that DCs are important sources of eddy kinetic energy in the deep ocean, key sites of energy dissipation, and potential contributors to episodes of strong near-bottom currents and sediment resuspension known as &#8220;benthic storms&#8221;. In the western North Atlantic, DCs that form within GS meander troughs could play a role in the Atlantic meridional overturning circulation by providing a path for recirculation of water between the Deep Western Boundary Current (DWBC) and the adjacent oceanic basins. However, most numerical ocean models lack the vertical resolution that is needed to simulate in detail both the vertical structure of DCs and the near-bottom flows.In this study, we configure the MIT general circulation model to produce eddy-rich simulations of western North Atlantic circulation at a horizontal resolution of 1/20o and with high vertical resolution (550 levels with uniform Dz = 10 m). Emphasis is placed on the role of DCs in the time-mean abyssal circulation and on their contribution to Lagrangian transport, particularly to the exchange of water between the DWBC and the adjacent basins and between the bottom mixed layer and the stratified interior. In the simulations, deep cyclones are found to form west of the New England seamounts, consistent with field observations from SYNOP. They also form in the Sohm abyssal plain &#8211; east of the seamounts &#8211; although observations are lacking to confirm or refute this result. In our simulations, the DCs typically persist for 30-90 days and move eastward a
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OtherLi J, Prentice IC, 2025,
How deep-time climate change has influenced the diversity of plants
<jats:p>Biodiversity loss and climate change are interlinked crises with global ecological and societal impacts. Common explanations for how climate shapes biodiversity focus either on spatial scale (whereby more extensive and/or isolated climates promote species richness) or on temporal scale (whereby older, or more stable, climates foster biodiversity). However, these hypotheses overlook the intrinsic link between the spatial and temporal dimensions of climate.We investigated how spatio-temporal climate changes over deep time may have influenced global patterns of plant diversity through the lens of climate analogues. By compiling global occurrence records for 350,864 vascular plant species, we produced the most comprehensive and precise global map of plant diversity to date. We identified analogues of recent (1851&#8211;1989) climate conditions across several geohistorical time periods: the Early Eocene (ca. 50 Ma), the Mid-Pliocene (3.3&#8211;3.0 Ma), the Last Glacial Maximum (LGM, 22&#8211;18 ka) and the Mid-Holocene (ca. 6 ka). We quantified spatial climate change within temporal periods, temporal change across spatial gradients, and the integrated spatio-temporal dynamics of climate. We evaluated the relative contributions of these metrics in explaining global plant diversity variation and examined the correlations between the spatial and temporal dimensions of climate change.Our findings extend previous hypotheses by showing that species richness is higher in climatic conditions that were historically more extensive and/or isolated and have remained so through time. We also reveal a previously unrecognized mechanism by which climatic conditions that have undergone geographic expansion and slower movement over deep time tend to harbour higher plant diversity. Moreover, the combination of temperature stability and precipitation variability has facilitated species accumulation in low-latitude regions.Spatial and temporal dimensions
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Journal articleKan W, Gao Y, Zhu Y, et al., 2025,
Genome-wide identification and expression analysis of TaFDL gene family responded to vernalization in wheat (Triticum aestivum L.).
, BMC Genomics, Vol: 26BACKGROUND: FLOWERING LOCUS D (FD) is a basic leucine zipper (bZIP) transcription factor known to be crucial in vernalization, flowering, and stress response across a variety of plants, including biennial and winter annual species. The TaFD-like (TaFDL) gene in wheat is the functional homologue of Arabidopsis FD, yet research on the TaFDL gene family in wheat is still lacking. RESULTS: In this study, a total of 62 TaFDL gene family members were identified and classified into 4 main subfamilies, and these genes were located on 21 chromosomes. A comprehensive analysis of the basic physicochemical properties, gene structure, conservation motif, conserved domain, and advanced protein structure of TaFDL gene family revealed the conservation among its individual subfamily. The family members underwent purifying selection. The segmental duplication events were the main driving force behind the expansion of the TaFDL gene family. The TaFDL gene family underwent differentiation in the evolution of FD genes. Additionally, the subcellular localization and transcriptional activation activities of five key TaFDL members were demonstrated. Gene Ontology (GO) annotations and promoter cis-regulatory element analysis indicated that the TaFDL members may play potential roles in regulating flowering, hormone response, low-temperature response, light response, and stress response, which were verified by transcriptome data analysis. Specifically, quantitative real-time PCR (qRT-PCR) analysis revealed that five TaFDL genes exhibited differential responses to different vernalization conditions in winter wheat seeding. Finally, the homologous genes of the five key TaFDL genes across nine different wheat cultivars highlight significant genetic diversity. CONCLUSION: These findings enrich the research on FD and its homologous genes, providing valuable insights into the TaFDL gene family's response to vernalization.
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Journal articleBenjamin S, Taylor ME, Drickamer K, 2025,
Application of a human lectin array to rapid in vitro screening of sugar-based epitopes that can be used as targeting tags for therapeutics
, GLYCOBIOLOGY, Vol: 35, ISSN: 0959-6658 -
Journal articlePotapova N, Whitford H, Hodge J, et al., 2025,
Optimal weight loss of pink pigeon (Nesoenas mayeri) eggs during incubation
, Zoo Biology, ISSN: 0733-3188Incubation of pink pigeon (Nesoenas mayeri) eggs under foster doves is an important element of the captive breeding program for this threatened species, and determining optimal species-specific incubation conditions could help to maximize hatchability. We analyzed 7 years of records (n = 104 eggs) from a captive collection to investigate whether the existing guideline for optimal total weight loss of 15% is appropriate for the pink pigeon. Successfully hatched eggs lost on average 14% of their initial mass during incubation, while a weight loss of 15.5% was associated with embryo mortality, and successful eggs lost slightly less weight per day, both as raw weight and as percentage of fresh weight. Eggs weighing at least 14 g at laying were significantly more likely to hatch than lighter eggs, indicating that low fresh weight may be the most useful predictor of embryo death in pink pigeons.
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Journal articleWitwicka A, Lopez-Osorio F, Arce A, et al., 2025,
Acute and chronic pesticide exposure trigger fundamentally different molecular responses in bumble bee brains
, BMC BIOLOGY, Vol: 23- Cite
- Citations: 3
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Journal articleEhsan M, Ghani L, Lan B, et al., 2025,
Unsymmetric triazine‐based triglucoside detergents for membrane protein stability
, ChemBioChem: a European journal of chemical biology, Vol: 26, ISSN: 1439-4227Membrane proteins play a crucial role in a variety of biological processes and are key targets for pharmaceutical development. Structural studies of membrane proteins provide molecular insights into the mechanisms of these processes and are essential for effective drug discovery. Historically, these studies have relied on solubilization of the target protein using detergents, but conventional detergents often fail to maintain the stability of challenging membrane proteins. To address this issue, there is a need to develop novel detergents with enhanced protein stabilization properties. In this study, we synthesized unsymmetric variants of recently reported tris(hydroxymethyl)aminomethane(TRIS)-linker-bearing triazine-based triglucosides (TTGs) by incorporating two different alkyl chains (long and short) into the detergent structure. When tested with model membrane proteins, including a G protein-coupled receptor, TTG-8,12 demonstrated superior efficacy in stabilizing membrane proteins compared to the original TTGs and the gold standard detergents DDM/LMNG. These results suggest that detergent unsymmetry is an important concept for improving detergent performance and unsymmetric detergents such as TTG-8,12 hold significant potential for advancing membrane protein structural studies.
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Journal articleGaboriau T, Tobias JA, Silvestro D, et al., 2025,
Exploring the macroevolutionary signature of asymmetric inheritance at speciation
, Systematic Biology, Vol: 74, Pages: 267-281, ISSN: 1063-5157Popular comparative phylogenetic models such as Brownian Motion, Ornstein-Ulhenbeck, and their extensions assume that, at speciation, a trait value is inherited identically by 2 descendant species. This assumption contrasts with models of speciation at a micro-evolutionary scale where descendants’ phenotypic distributions are sub-samples of the ancestral distribution. Different speciation mechanisms can lead to a displacement of the ancestral phenotypic mean among descendants and an asymmetric inheritance of the ancestral phenotypic variance. In contrast, even macro-evolutionary models that account for intraspecific variance assume symmetrically conserved inheritance of ancestral phenotypic distribution at speciation. Here, we develop an Asymmetric Brownian Motion model (ABM) that relaxes the assumption of symmetric and conserved inheritance of the ancestral distribution at the time of speciation. The ABM jointly models the evolution of both intra- and inter-specific phenotypic variation. It also infers the mode of phenotypic inheritance at speciation, which can range from a symmetric and conserved inheritance, where descendants inherit the ancestral distribution, to an asymmetric and displaced inheritance, where descendants inherit divergent phenotypic means and variances. To demonstrate this model, we analyze the evolution of beak morphology in Darwin finches, finding evidence of displacement at speciation. The ABM model helps to bridge micro- and macro-evolutionary models of trait evolution by providing a more robust framework for testing the effects of ecological speciation, character displacement, and niche partitioning on trait evolution at the macro-evolutionary scale.
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Journal articleMengoli G, Sandy P H, Prentice IC, 2025,
The response of carbon uptake to soil moisture stress: adaptation to climatic aridity
, Global Change Biology, Vol: 31, ISSN: 1354-1013The coupling between carbon uptake and water loss through stomata implies that gross primary production (GPP) can be limited by soil water availability through reduced leaf area and/or stomatal conductance. Ecosystem and land-surface models commonly assume that GPP is highest under well-watered conditions and apply a stress function to reduce GPP as soil moisture declines. Optimality considerations, however, suggest that the stress function should depend on climatic aridity: ecosystems adapted to more arid climates should use water more conservatively when soil moisture is high, but maintain unchanged GPP down to a lower critical soil-moisture threshold. We use eddy-covariance flux data to test this hypothesis. We investigate how the light-use efficiency (LUE) of GPP depends on soil moisture across ecosystems representing a wide range of climatic aridity. ‘Well-watered’ GPP is estimated using the sub-daily P model, a first-principles LUE model driven by atmospheric data and remotely sensed vegetation cover. Breakpoint regression is used to relate daily β(θ) (the ratio of flux data–derived GPP to modelled well-watered GPP) to soil moisture estimated via a generic water balance model. The resulting piecewise function describing β(θ) varies with aridity, as hypothesised. Unstressed LUE, even when soil moisture is high, declines with increasing aridity index (AI). So does the critical soil-moisture threshold. Moreover, for any AI value, there exists a soil moisture level at which β(θ) is maximised. This level declines as AI increases. This behaviour is captured by universal non-linear functions relating both unstressed LUE and the critical soil-moisture threshold to AI. Applying these aridity-based functions to predict the site-level response of LUE to soil moisture substantially improves GPP simulation under both water-stressed and unstressed conditions, suggesting a route towards a robust, universal model representati
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Journal articleStark KA, Clegg T, Bernhardt JR, et al., 2025,
Toward a More Dynamic Metabolic Theory of Ecology to Predict Climate Change Effects on Biological Systems
, AMERICAN NATURALIST, Vol: 205, Pages: 285-305, ISSN: 0003-0147- Cite
- Citations: 1
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Journal articleZHOU B, Cai W, Zhu Z, et al., 2025,
A general model for the seasonal to decadal dynamics of leaf area
, Global Change Biology, Vol: 31, ISSN: 1354-1013Leaf phenology, represented at the ecosystem scale by the seasonal dynamics of leaf area index (LAI), is a key control on the exchanges of CO2, energy, and water between the land and atmosphere. Robust simulation of leaf phenology is thus important for both dynamic global vegetation models (DGVMs) and land-surface representations in climate and Earth System models. There is no general agreement on how leaf phenology should be modeled. However, a recent theoretical advance posits a universal relationship between the time course of “steady-state” gross primary production (GPP) and LAI—that is, the mutually consistent LAI and GPP that would pertain if weather conditions were held constant. This theory embodies the concept that leaves should be displayed when their presence is most beneficial to plants, combined with the reciprocal relationship of LAI and GPP via (a) the Beer's law dependence of GPP on LAI, and (b) the requirement for GPP to support the allocation of carbon to leaves. Here we develop a global prognostic LAI model, combining this theoretical approach with a parameter-sparse terrestrial GPP model (the P model) that achieves a good fit to GPP derived from flux towers in all biomes and a scheme based on the P model that predicts seasonal maximum LAI as the lesser of an energy-limited rate (maximizing GPP) and a water-limited rate (maximizing the use of available precipitation). The exponential moving average method is used to represent the time lag between leaf allocation and modeled steady-state LAI. The model captures satellite-derived LAI dynamics across biomes at both site and global levels. Since this model outperforms the 15 DGVMs used in the TRENDY project, it could provide a basis for improved representation of leaf-area dynamics in vegetation and climate models.
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Journal articleQi M, Taunt H, Bečková M, et al., 2025,
Enhancing the production of chlorophyll f in the cyanobacterium Synechocystis sp. PCC 6803
, Physiologia Plantarum, Vol: 177, ISSN: 0031-9317One potential approach to improve the productivity of cyanobacteria and microalgae is to enhance photosynthetic efficiency by introducing far-red absorbing pigment molecules (such as chlorophylls f and d) into the photosynthetic apparatus to expand the range of photosynthetically active radiation. We have shown previously that expressing the ChlF subunit of Chroococcidiopsis thermalis PCC 7203 in the model cyanobacterium Synechocystis sp. PCC 6803 (Syn6803) is sufficient to drive the production of chlorophyll f (Chl f), but only to low levels (0.24% Chl f/Chl a). By using the strong Pcpc560 promoter and an N-terminal truncated derivative of ChlF, we have been able to increase the yield of Chl f in white light by over 30-fold to about 8.2% Chl f/Chl a, close to the level displayed by far-red photoacclimated C. thermalis 7203. Additionally, we demonstrate that ChlF from Fisherella thermalis PCC 7521, like ChlF from C. thermalis 7203, assembles into a variant of the monomeric photosystem II (PSII) core complex termed the super-rogue PSII complex when expressed in Syn6803. This contrasts with the originally reported formation of a ChlF homodimeric complex in Synechococcus sp. PCC 7002. Overall, our work is an important starting point for mechanistic and structural studies of super-rogue PSII and for incorporating Chl f into the photosynthetic apparatus of Syn6803.
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Journal articleRen Y, Wang H, Harrison SP, et al., 2025,
Incorporating the acclimation of photosynthesis and leaf respiration in the Noah-MP land surface model: model development and evaluation
, Journal of Advances in Modeling Earth Systems, Vol: 17, ISSN: 1942-2466Realistic simulation of leaf photosynthetic and respiratory processes is needed for accurate prediction of the global carbon cycle. These two processes systematically acclimate to long-term environmental changes by adjusting photosynthetic and respiratory traits (e.g., the maximum photosynthetic capacity at 25°C (Vcmax,25) and the leaf respiration rate at 25°C (R25)) following increasingly well-understood principles. While some land surface models (LSMs) now account for thermal acclimation, they do so by assigning empirical parameterizations for individual plant functional types (PFTs). Here, we have implemented an Eco-Evolutionary Optimality (EEO)-based scheme to represent the universal acclimation of photosynthesis and leaf respiration to multiple environmental effects, and that therefore requires no PFT-specific parameterizations, in a standard version of the widely used LSM, Noah MP. We evaluated model performance with plant trait data from a 5-year experiment and extensive global field measurements, and carbon flux measurements from FLUXNET2015. We show that observed R25 and Vcmax,25 vary substantially both temporally and spatially within the same PFT (C.V. >20%). Our EEO-based scheme captures 62% of the temporal and 70% of the spatial variations in Vcmax,25 (73% and 54% of the variations in R25). The standard scheme underestimates gross primary production by 10% versus 2% for the EEO-based scheme and generates a larger spread in r (correlation coefficient) across flux sites (0.79 ± 0.16 vs. 0.84 ± 0.1, mean ± S.D.). The standard scheme greatly overestimates canopy respiration (bias: ∼200% vs. 8% for the EEO scheme), resulting in less CO2 uptake by terrestrial ecosystems. Our approach thus simulates climate-carbon coupling more realistically, with fewer parameters.
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Journal articleYu C, Zheng J, Zhang Y, et al., 2025,
Towards sustainable spirulina farming: Enhancing productivity and biosafety with a salinity-biostimulants strategy
, BIORESOURCE TECHNOLOGY, Vol: 419, ISSN: 0960-8524 -
Journal articleCorley MK, Cosme LV, Armbruster PA, et al., 2025,
Population Structure of the Invasive Asian Tiger Mosquito, <i>Aedes albopictus</i>, in Europe
, ECOLOGY AND EVOLUTION, Vol: 15, ISSN: 2045-7758 -
Journal articleFerrando-Marco M, Barkoulas M, 2025,
EFL-3/E2F7 modulates Wnt signalling by repressing the Nemo-like kinase LIT-1 during asymmetric epidermal cell division in <i>Caenorhabditis elegans</i>
, DEVELOPMENT, Vol: 152, ISSN: 0950-1991 -
Journal articleChen T, Hojka M, Davey P, et al., 2025,
Engineering Rubisco condensation in chloroplasts to manipulate plant photosynthesis
, Plant Biotechnology Journal, ISSN: 1467-7644 -
Journal articleBalducci MG, Calevo J, Duffy KJ, 2025,
Orchid Mycorrhizal Communities Associated With <i>Orchis italica</i> Are Shaped by Ecological Factors and Geographical Gradients
, JOURNAL OF BIOGEOGRAPHY, Vol: 52, Pages: 544-557, ISSN: 0305-0270- Cite
- Citations: 1
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Journal articleRay NE, Bonaglia S, Cavan EL, et al., 2025,
Biogeochemical consequences of marine fisheries and aquaculture
, NATURE REVIEWS EARTH & ENVIRONMENT, Vol: 6, Pages: 163-177- Cite
- Citations: 4
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Journal articleFieldwalker A, Patel R, Zhao L, et al., 2025,
A Parallel Human and Rat Investigation of the Interaction Between Descending and Spinal Modulatory Mechanisms
, EUROPEAN JOURNAL OF PAIN, Vol: 29, ISSN: 1090-3801 -
Journal articleGlymenaki M, Curio S, Shrestha S, et al., 2025,
Roux-en-Y gastric bypass-associated fecal tyramine promotes colon cancer risk via increased DNA damage, cell proliferation and inflammation
, Microbiome, Vol: 13, ISSN: 2049-2618BackgroundFecal abundances of Enterobacteriaceae and Enterococcaceae are elevated in patients following Roux-en-Y gastric bypass (RYGB) surgery. Concurrently, fecal concentrations of tyramine, derived from gut bacterial metabolism of tyrosine and/or food, increased post-RYGB. Furthermore, emerging evidence suggests that RYGB is associated with increased colorectal cancer (CRC) risk. However, the causal link between RYGB-associated microbial metabolites and CRC risk remains unclear. Hence, this study investigated the tyrosine metabolism of Enterobacteriaceae and Enterococcaceae strains isolated from patients post-RYGB and explored the causal effects of tyramine on the CRC risk and tumorigenesis using both human colonic cancer cell line (HCT 116) and wild-type and ApcMin/+ mice.ResultsWe isolated 31 bacterial isolates belonging to Enterobacteriaceae and Enterococcaceae families from the feces of patients with RYGB surgery. By culturing the isolates in tyrosine-supplemented medium, we found that Citrobacter produced phenol as a main product of tyrosine, whereas Enterobacter and Klebsiella produced 4-hydroxyphenylacetate, Escherichia produced 4-hydroxyphenyllactate and 4-hydroxyphenylpyruvate, and Enterococcus and two Klebsiella isolates produced tyramine. These observations suggested the gut bacterial contribution to increased fecal concentrations of tyramine post-RYGB. We subsequently evaluated the impact of tyramine on CRC risk and development. Tyramine induced necrosis and promoted cell proliferation and DNA damage of HCT 116 cells. Daily oral administration of tyramine for 49 days to wild-type mice resulted in visible adenomas in 5 out of 12 mice, accompanied by significantly enhanced DNA damage (γH2AX +) and an increased trend of cell proliferation (Ki67 +) in the ileum, along with an upregulated expression of the cell division cycle gene (Cdc34b) in the colon. To evaluate the impact of tyramine on intestinal tumor growth, we treated ApcMin/+ m
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Thesis dissertationSabey D, 2025,
Characterising Nucleolar Architecture in Trypanosoma brucei
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