BibTex format
@article{Okumu:2026:10.1016/j.pt.2026.03.010,
author = {Okumu, FO and Finda, M and Odero, JO and Aboagye-Antwi, F and Adeogun, A and Atta-Obeng, C and Baldini, F and Bouyer, J and Burkot, TR and Churcher, TS and Dadzie, SK and Diabaté, A and Ferguson, HM and Govella, NJ and Habtewold, T and Hancock, PA and Kahamba, N and Kaindoa, EW and Kayondo, JK and Lawniczak, MKN and Lobo, NF and Lwetoijera, D and Maiga, H and Marrenjo, D and Marshall, JM and Matoke-Muhia, D and Mgaya, JN and Msaky, DS and Urio, N and Munhenga, G and Muyaga, L and Mwalimu, CD and Mwanga, EP and Ngowo, H and Ochomo, E and Ogoma, S and Okonjo, E and Opiyo, M and Ramaita, E and Reddy, MR and Salum, S and Santos, M and Sedda, L and Seethaler, T and Selvaraj, P and Sikulu-Lord, MT and Siria, D and Tarimo, B and Tatarsky, A and Tchouakui, M and Thomsen, EK and Tonui, W and Tripet, F and Wiener, S and Windbichler, N and Wondji, CS and Nolan, T and James, S},
doi = {10.1016/j.pt.2026.03.010},
journal = {Trends in Parasitology},
pages = {463--493},
title = {Adapting Africa's vector surveillance systems to monitor gene-drive mosquitoes in malaria control},
url = {http://dx.doi.org/10.1016/j.pt.2026.03.010},
volume = {42},
year = {2026}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - Gene-drive mosquitoes could transform malaria control in Africa, but their rapid, autonomous spread requires rigorous post-release monitoring. Most malaria-endemic countries already conduct some entomological surveillance, although it is often limited, fragmented, and externally funded. Molecular diagnostics are also expanding but remain mostly research focused and ad hoc. These imperfect systems offer workable foundations for strategic upgrades to support essential gene-drive monitoring. Priority investments should strengthen field-entomology, high-throughput genotyping for drive alleles and resistance, technical expertise, and integrated data for decision-making. Fortunately, first-generation gene drives already align with common phenotyping and genotyping workflows, avoiding major infrastructure overhauls, and permit simpler evaluation metrics than conventional interventions. This feature review examines key technical and operational considerations for monitoring gene drives and recommends how countries can adapt their vector surveillance systems to effectively monitor gene-drive mosquito releases.
AU - Okumu,FO
AU - Finda,M
AU - Odero,JO
AU - Aboagye-Antwi,F
AU - Adeogun,A
AU - Atta-Obeng,C
AU - Baldini,F
AU - Bouyer,J
AU - Burkot,TR
AU - Churcher,TS
AU - Dadzie,SK
AU - Diabaté,A
AU - Ferguson,HM
AU - Govella,NJ
AU - Habtewold,T
AU - Hancock,PA
AU - Kahamba,N
AU - Kaindoa,EW
AU - Kayondo,JK
AU - Lawniczak,MKN
AU - Lobo,NF
AU - Lwetoijera,D
AU - Maiga,H
AU - Marrenjo,D
AU - Marshall,JM
AU - Matoke-Muhia,D
AU - Mgaya,JN
AU - Msaky,DS
AU - Urio,N
AU - Munhenga,G
AU - Muyaga,L
AU - Mwalimu,CD
AU - Mwanga,EP
AU - Ngowo,H
AU - Ochomo,E
AU - Ogoma,S
AU - Okonjo,E
AU - Opiyo,M
AU - Ramaita,E
AU - Reddy,MR
AU - Salum,S
AU - Santos,M
AU - Sedda,L
AU - Seethaler,T
AU - Selvaraj,P
AU - Sikulu-Lord,MT
AU - Siria,D
AU - Tarimo,B
AU - Tatarsky,A
AU - Tchouakui,M
AU - Thomsen,EK
AU - Tonui,W
AU - Tripet,F
AU - Wiener,S
AU - Windbichler,N
AU - Wondji,CS
AU - Nolan,T
AU - James,S
DO - 10.1016/j.pt.2026.03.010
EP - 493
PY - 2026///
SN - 1471-4922
SP - 463
TI - Adapting Africa's vector surveillance systems to monitor gene-drive mosquitoes in malaria control
T2 - Trends in Parasitology
UR - http://dx.doi.org/10.1016/j.pt.2026.03.010
VL - 42
ER -