BibTex format

author = {Tyrrell, J and Boutelle, M and Campbell, A},
doi = {10.1002/adfm.202007086},
journal = {Advanced Functional Materials},
pages = {1--12},
title = {Measurement of electrophysiological signals in vitro using high-performance organic electrochemical transistors},
url = {},
volume = {31},
year = {2021}

RIS format (EndNote, RefMan)

AB - Biological environments use ions in charge transport for information transmission. The properties of mixed electronic and ionic conductivity in organic materials make them ideal candidates to transduce physiological information into electronically processable signals. A device proven to be highly successful in measuring such information is the organic electrochemical transistor (OECT). Previous electrophysiological measurements performed using OECTs show superior signaltonoise ratios than electrodes at low frequencies. Subsequent development has significantly improved critical performance parameters such as transconductance and response time. Here, interdigitatedelectrode OECTs are fabricated on flexible substrates, with one such stateoftheart device achieving a peak transconductance of 139 mS with a 138 µs response time. The devices are implemented into an array with interconnects suitable for microelectrocorticographic application and eight architecture variations are compared. The two bestperforming arrays are subject to the full electrophysiological spectrum using prerecorded signals. With frequency filtering, kHzscale frequencies with 10 µVscale voltages are resolved. This is supported by a novel quantification of the noise, which compares the gate voltage input and drain current output. These results demonstrate that highperformance OECTs can resolve the full electrophysiological spectrum and suggest that superior signaltonoise ratios could be achieved in high frequency measurements of multiunit activity.
AU - Tyrrell,J
AU - Boutelle,M
AU - Campbell,A
DO - 10.1002/adfm.202007086
EP - 12
PY - 2021///
SN - 1616-301X
SP - 1
TI - Measurement of electrophysiological signals in vitro using high-performance organic electrochemical transistors
T2 - Advanced Functional Materials
UR -
UR -
UR -
VL - 31
ER -