We are seeking to recruit an outstanding structural biologist to join the group of Dr Maruf Ali, Department of Life Sciences. The successful candidate will join a team of researchers investigating structure and mechanism of molecular chaperone complexes involved in protein homeostasis and stress signaling. Methodology will include cryo-electron microscopy (EM) and a suite of biophysical, biochemical and cellular assays to determine structure...
Job listing information
- Reference NAT00509
- Date posted 14 August 2019
- Closing date 18 September 2019
We are seeking to recruit an outstanding structural biologist to join the group of Dr Maruf Ali, Department of Life Sciences. The successful candidate will join a team of researchers investigating structure and mechanism of molecular chaperone complexes involved in protein homeostasis and stress signaling. Methodology will include cryo-electron microscopy (EM) and a suite of biophysical, biochemical and cellular assays to determine structure and function. The position is funded by Cancer research UK.
Duties and responsibilities
The successful candidate will be expected to take a leading role in studying molecular chaperone complexes that regulate protein homeostasis and stress signalling. Structure and functional studies will be undertaken with an emphasis on taking advantage of the recent resolution revolution in cryo-EM. At times, you will mentor junior biochemists/structural biologists in our research team. The successful candidate will join the world-leading Departments of Life Sciences and Centre for Structural Biology here at Imperial College. We are superbly equipped for undertaking cryo-EM with three screening microscopes and a Tecnai F20 with direct electron detector. Routine Titan Krios data collection is available through Block Allocation Group (BAG) access to the Electron Bio-Imaging Centre (eBIC, Diamond) and the LonCEM consortium (Crick Institute, Autumn 2019).
You must hold a PhD or equivalent in structural biology (either X-ray or cryo-EM). Experience in the workflow for structure determination, including protein expression/purification, biochemical analysis, data collection is required. Experience in cryo-EM and tissue culture is advantageous.
Also, you must demonstrate a strong research track record as evidenced by publications in international journals.You must have excellent verbal, written communication and organization skills, a creative approach to problem-solving and the ability to develop and apply new concepts. You must also be self-motivated and have the ability to develop and manage complex experimental protocols.
This is a full-time, fixed-term appointment available for up to 30 months with an immediate start.
*Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £35,477- £38,566 per annum
Should you have any queries about the application process please contact us by email at firstname.lastname@example.org
Informal enquiries to Dr Maruf Ali: email@example.com
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