BibTex format
@article{Delgado-Ortiz:2024:10.1183/23120541.00673-2023,
author = {Delgado-Ortiz, L and Ranciati, S and Arbillaga-Etxarri, A and Balcells, E and Buekers, J and Demeyer, H and Frei, A and Gimeno-Santos, E and Hopkinson, NS and de, Jong C and Karlsson, N and Louvaris, Z and Palmerini, L and Polkey, MI and Puhan, MA and Rabinovich, RA and Rodríguez, Chiaradia DA and Rodriguez-Roisin, R and Toran-Montserrat, P and Vogiatzis, I and Watz, H and Troosters, T and Garcia-Aymerich, J},
doi = {10.1183/23120541.00673-2023},
journal = {ERJ Open Research},
title = {Real-world walking cadence in people with COPD},
url = {http://dx.doi.org/10.1183/23120541.00673-2023},
volume = {10},
year = {2024}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - Introduction The clinical validity of real-world walking cadence in people with COPD is unsettled. Our objective was to assess the levels, variability and association with clinically relevant COPD characteristics and outcomes of real-world walking cadence.Methods We assessed walking cadence (steps per minute during walking bouts longer than 10s) from 7days’ accelerometer data in 593 individuals with COPD from five European countries, and clinical and functional characteristics from validated questionnaires and standardised tests. Severe exacerbations during a 12-month follow-up were recorded from patient reports and medical registries.Results Participants were mostly male (80%) and had mean±sd age of 68±8years, post-bronchodilator forced expiratory volume in 1s (FEV1) of 57±19% predicted and walked 6880±3926steps·day−1. Mean walking cadence was 88±9steps·min−1, followed a normal distribution and was highly stable within-person (intraclass correlation coefficient 0.92, 95% CI 0.90–0.93). After adjusting for age, sex, height and number of walking bouts in fractional polynomial or linear regressions, walking cadence was positively associated with FEV1, 6-min walk distance, physical activity (steps·day−1, time in moderate-to-vigorous physical activity, vector magnitude units, walking time, intensity during locomotion), physical activity experience and health-related quality of life and negatively associated with breathlessness and depression (all p<0.05). These associations remained after further adjustment for daily steps. In negative binomial regression adjusted for multiple confounders, walking cadence related to lower number of severe exacerbations during follow-up (incidence rate ratio 0.94 per step·min−1, 95% CI 0.91–0.99, p=0.009).Conclusions Higher real-world walking cadence is associated with better COPD status and lower severe exacerbations risk, w
AU - Delgado-Ortiz,L
AU - Ranciati,S
AU - Arbillaga-Etxarri,A
AU - Balcells,E
AU - Buekers,J
AU - Demeyer,H
AU - Frei,A
AU - Gimeno-Santos,E
AU - Hopkinson,NS
AU - de,Jong C
AU - Karlsson,N
AU - Louvaris,Z
AU - Palmerini,L
AU - Polkey,MI
AU - Puhan,MA
AU - Rabinovich,RA
AU - Rodríguez,Chiaradia DA
AU - Rodriguez-Roisin,R
AU - Toran-Montserrat,P
AU - Vogiatzis,I
AU - Watz,H
AU - Troosters,T
AU - Garcia-Aymerich,J
DO - 10.1183/23120541.00673-2023
PY - 2024///
SN - 2312-0541
TI - Real-world walking cadence in people with COPD
T2 - ERJ Open Research
UR - http://dx.doi.org/10.1183/23120541.00673-2023
UR - https://www.ncbi.nlm.nih.gov/pubmed/38444656
UR - https://openres.ersjournals.com/content/10/2/00673-2023
VL - 10
ER -