BibTex format
@article{Sousa-Pinto:2025:10.1080/25310429.2025.2532980,
author = {Sousa-Pinto, B and Schleich, F and Louis, G and Gemicioglu, B and Kvedariene, V and Regateiro, FS and Chaves, Loureiro C and Taborda-Barata, L and Amaral, R and Anto, JM and Bedbrook, A and Czarlewski, W and Ansotegui, IJ and Bergmann, K-C and Bonini, M and Bossios, A and Boulet, L-P and Braido, F and Brightling, C and Brusselle, G and Brussino, L and Canonica, GW and Cruz, AA and Haahtela, T and Heaney, LG and Hyland, M and Ivancevich, JC and Klimek, L and Kulus, M and Kuna, P and Kupczyk, M and Larenas-Linnemann, DE and Makris, M and Marques-Cruz, M and Gil-Mata, S and Morais-Almeida, M and Niedoszytko, M and Ollert, M and Papadopoulos, NG and Patella, V and Pfaar, O and Porsbjerg, C and Puggioni, F and Quirce, S and Robalo, Cordeiro C and Roche, N and Samolinski, B and Sastre, J and Scichilone, N and Skrgat, S and Toppila-Salmi, S and Usmani, OS and Valiulis, A and Gradauskiene, B and Koyuncu, IV and Ventura, MT and Vieira, RJ and Yorgancioglu, A and Fonseca, JA and Zuberbier, T and},
doi = {10.1080/25310429.2025.2532980},
journal = {Pulmonology},
title = {Daily digital biomarkers in the follow-up and clustering of patients with asthma},
url = {http://dx.doi.org/10.1080/25310429.2025.2532980},
volume = {31},
year = {2025}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - Background and Research questionWe aimed to assess whether levels of digital biomarkers can reflect monthly patterns of asthma controlStudy design and methodsWe performed a longitudinal study on patients with asthma and comorbid rhinitis who filled ≥26 days of data in a month in the MASK-air® app and who reported at least 1 day of treatment with an inhaled corticosteroid with or without a long-acting β2-agonist (ICS ± LABA). We applied k-means cluster analysis to define clusters of months according to daily asthma control and medication use. Clusters were compared using digital biomarkers (visual analogue scale [VAS] on asthma symptoms and electronic daily asthma control score [e-DASTHMA]). We compared patients who did not switch with patients who switched their ICS ± LABA.ResultsWe assessed 243 patients and 1358 months. We identified three clusters of poor asthma control despite high ICS ± LABA adherence, one cluster of poor asthma control and poor ICS ± LABA adherence, one cluster of good asthma control and high ICS ± LABA adherence and one cluster of good asthma control despite poor ICS ± LABA adherence. These clusters displayed relevant differences in VAS asthma and e-DASTHMA levels. Similar clusters were found in ‘non-switchers’ versus ‘switchers’.ConclusionLevels of digital biomarkers reflect asthma control patterns and might be used to monitor patients with asthma.
AU - Sousa-Pinto,B
AU - Schleich,F
AU - Louis,G
AU - Gemicioglu,B
AU - Kvedariene,V
AU - Regateiro,FS
AU - Chaves,Loureiro C
AU - Taborda-Barata,L
AU - Amaral,R
AU - Anto,JM
AU - Bedbrook,A
AU - Czarlewski,W
AU - Ansotegui,IJ
AU - Bergmann,K-C
AU - Bonini,M
AU - Bossios,A
AU - Boulet,L-P
AU - Braido,F
AU - Brightling,C
AU - Brusselle,G
AU - Brussino,L
AU - Canonica,GW
AU - Cruz,AA
AU - Haahtela,T
AU - Heaney,LG
AU - Hyland,M
AU - Ivancevich,JC
AU - Klimek,L
AU - Kulus,M
AU - Kuna,P
AU - Kupczyk,M
AU - Larenas-Linnemann,DE
AU - Makris,M
AU - Marques-Cruz,M
AU - Gil-Mata,S
AU - Morais-Almeida,M
AU - Niedoszytko,M
AU - Ollert,M
AU - Papadopoulos,NG
AU - Patella,V
AU - Pfaar,O
AU - Porsbjerg,C
AU - Puggioni,F
AU - Quirce,S
AU - Robalo,Cordeiro C
AU - Roche,N
AU - Samolinski,B
AU - Sastre,J
AU - Scichilone,N
AU - Skrgat,S
AU - Toppila-Salmi,S
AU - Usmani,OS
AU - Valiulis,A
AU - Gradauskiene,B
AU - Koyuncu,IV
AU - Ventura,MT
AU - Vieira,RJ
AU - Yorgancioglu,A
AU - Fonseca,JA
AU - Zuberbier,T
AU - Petre,B
AU - Louis,R
AU - Bousquet,J
DO - 10.1080/25310429.2025.2532980
PY - 2025///
SN - 2531-0429
TI - Daily digital biomarkers in the follow-up and clustering of patients with asthma
T2 - Pulmonology
UR - http://dx.doi.org/10.1080/25310429.2025.2532980
UR - https://www.tandfonline.com/doi/full/10.1080/25310429.2025.2532980
VL - 31
ER -