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Conference paperDiop A, Hughes R, Muellerova H, et al., 2025,
Differences in the Characteristics and Outcomes by Sex in Patients With Physician-diagnosed Asthma and/or COPD in the NOVELTY Study
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Conference paperHughes R, McKellar D, Arad N, et al., 2025,
Coving Index: A Novel, Sensitive Spirometric Marker of Small Airways Obstruction10.1164/ajrccm.2025.211.Abstracts.A2566
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Conference paperSmall PM, Rudd M, Galvosas M, et al., 2025,
Evaluating Cough Bouts as a Metric for Cough Severity
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Conference paperPrice DB, Dickens A, Henley W, et al., 2025,
Offering Digital Adherence Support Improves Clinical Outcomes for High-Risk Chronic Obstructive Pulmonary Disease (COPD) Patients With Poor Adherence to Inhaled Therapy
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Conference paperDoe G, Taylor SJC, Edwards G, et al., 2025,
"Help Humans Make the Right Decisions." Patient Perspectives on Artificial Intelligence (AI) Supporting Clinicians in the Interpretation of Spirometry: A Qualitative Study
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Journal articleValencia-Hernández CA, Yu Z, Gehring U, et al., 2025,
Residential greenspace and lung function throughout childhood and adolescence in five European birth cohorts. A CADSET initiative
, Environment International, Vol: 199, ISSN: 0160-4120Whether greenspace affects lung function is unclear. We explored associations between the level of greenness or presence of urban green space near the home with lung function measures taken repeatedly during childhood and adolescence in five European birth cohorts.Lung function was measured by spirometry between six and 22 years (2–3 times), and 9,206 participants from BAMSE (Sweden), GINI/LISA South and GINI/LISA North (Germany), PIAMA (The Netherlands) and INMA (Spain) contributed at least one lung function measurement. The mean Normalized Difference Vegetation Index (NDVI) in a 300 m buffer and presence of urban green space within a 300 m buffer (yes/no) were estimated at the home address at the time of each spirometry measurement. Cohort-specific associations were assessed using adjusted linear mixed models and combined in a random-effects meta-analysis.Residential greenness was not associated with forced expiratory volume in one second (FEV1), forced vital capacity (FVC) or FEV1/FVC in the meta-analysis (2.3 ml [-3.2, 7.9], 6.2 ml [-3.4, 15.7] and −0.1 [-0.3, 0.1] per 0.1 increase in NDVI, respectively), nor was having a nearby urban green space (−8.6 ml [–22.3, 5.0], −7.6 ml [-24.7, 9.4] and 0.0 [-0.4, 0.3], respectively). Heterogeneity was low to moderate (I2 = 0 –39 %). Asthma, atopy, air pollution, sex, socioeconomic status and urbanization did not modify the null associations.Using repeated data from five large independent European birth cohorts, we did not find associations between vegetation levels around the home or the presence of an urban green space and lung function levels during childhood and adolescence.
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Journal articleRothen-Rutishauser B, Darquenne C, Cipolla D, et al., 2025,
History of the International Society of Aerosols in Medicine (ISAM): Celebrating the 25th Congress
, JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, Vol: 38, Pages: 103-105, ISSN: 1941-2711 -
Conference paperChan R, Lipworth BJ, Berti A, et al., 2025,
Combined Point-of-Care Assessment Using Oscillometry, Spirometry, and FeNO to Optimally Identify an At-risk Asthma Phenotype
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Conference paperKimura H, Kermani NZ, Kimura N, et al., 2025,
CC16 Confers Protection Against Influenza a Virus Infection in Human Airway Epithelium
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Conference paperRaby KL, Gaffney E, Koranteng JB, et al., 2025,
Blood Eosinophil Gene Expression Phenotype Is Altered in Response to Anti-IL-5 Therapy Mepolizumab
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Conference paperBegg M, Pyle CJ, Patel N, et al., 2025,
APL-10456; An Adjuvanted Rhinovirus Clinical Vaccine Candidate Which Generates Cross-species Humoral and Th1-polarized Cellular Immunity
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Conference paperRaby KL, Li H, Dixey P, et al., 2025,
Mechanisms of Anti-IL5RαTherapy Restoring Nasal Epithelial Cell Barrier Function in Severe Eosinophilic Asthma
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Conference paperLong MB, Hull RC, Gilmour A, et al., 2025,
A Bispecific Monoclonal Antibody Targeting Psl and PcrV for Chronic Pseudomonas Aeruginosa Infection in Patients With Bronchiectasis: Results From a Randomized, Double-Blind Placebo-Controlled Trial (GREAT-2)
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Conference paperWalsh SL, Kanavati F, Montiero M, et al., 2025,
Deep Learning-Based Quantitative CT and CT Phenotype Classification Independently Predict Mortality in Idiopathic Pulmonary Fibrosis, a Prospective Observational Cohort Study
, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X -
Journal articleFinney LJ, Mah J, Duvall M, et al., 2025,
Select Airway Specialized Proresolving Mediators Are Associated with Recovery from Nonviral Chronic Obstructive Pulmonary Disease Exacerbations
, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 211, Pages: 803-813, ISSN: 1073-449X- Cite
- Citations: 1
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Journal articleBartlett-Pestell S, Wong T, Wedzicha JA, 2025,
Exacerbating the Problem: Chronic Obstructive Pulmonary Disease and Atrial Fibrillation
, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 211, Pages: 695-697, ISSN: 1073-449X- Cite
- Citations: 1
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Journal articleHuang M, Wen J, Lu C, et al., 2025,
Residential greenness, genetic susceptibility, and asthma risk: Mediating roles of air pollution in UK and Chinese populations
, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, Vol: 296, ISSN: 0147-6513 -
Journal articleDielesen J, Ledwaba-Chapman LJ, Kasetti P, et al., 2025,
Six early CPAP-usage behavioural patterns determine peak CPAP adherence and permit tailored intervention, in patients with obstructive sleep apnoea
, THORAX, Vol: 80, Pages: 300-308, ISSN: 0040-6376- Cite
- Citations: 4
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Journal articleZein JG, Zounemat-Kermani N, Adcock IM, 2025,
Development of an asthma health-care burden score as a measure of severity and predictor of remission in SARP III and U-BIOPRED: results from two major longitudinal asthma cohorts (vol 13, pg 35, 2025)
, LANCET RESPIRATORY MEDICINE, Vol: 13, Pages: e27-e27, ISSN: 2213-2600 -
Journal articleJia N, Jin M, Liu Y, et al., 2025,
The management of type 2 inflammatory respiratory diseases: a Chinese expert consensus [2024]
, Journal of Thoracic Disease, Vol: 17, Pages: 1807-1831, ISSN: 2072-1439Background: Type 2 (T2) inflammatory respiratory diseases encompass a range of conditions characterized by inflammation affecting the airways and lung parenchyma, with their pathogenesis rooted in T2 inflammation. Biological treatments that mitigate T2 inflammation revolutionize the therapeutic landscape for these respiratory diseases. However, there are decision-making difficulties in terms of the target population, timing of initiation, and type selection for biological targeted therapy. Methods: Search strategies were focused on relevant issues related to T2 inflammatory respiratory diseases from PubMed with search date from 2014 to 2024. The quality of evidence and grading recommendations were assessed with the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. Consensus was achieved through two rounds of anonymous voting with a strong recommendation demanding at least 70% approval from the participants. Results: A total of 370 basic research results and clinical evidence-based medical data were collected and reviewed. The latest research advances, clinical evidence, and expert insights relating to the use of biological treatments aiming at T2 inflammation in respiratory diseases and their co-morbidities were discussed rigorously and iteratively by an expert panel, and a consensus report with recommendations is presented. Conclusions: This consensus outlines the pathogenesis, assessment of T2 inflammation, biological therapies targeted at T2 inflammation, and management strategies for T2 inflammatory respiratory diseases and their comorbidities. It will serve as a valuable guide for clinicians in China, empowering them to diagnose and manage these conditions more effectively.
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