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Journal articleLiu G, Hsu AC, Geirnaert S, et al., 2025,
Vitronectin regulates lung tissue remodeling and emphysema in chronic obstructive pulmonary disease
, MOLECULAR THERAPY, Vol: 33, Pages: 917-932, ISSN: 1525-0016- Cite
- Citations: 2
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Journal articleMatera MG, Calzetta L, Rinaldi B, et al., 2025,
Animal models of chronic obstructive pulmonary disease and their role in drug discovery and development: a critical review
, EXPERT OPINION ON DRUG DISCOVERY, Vol: 20, Pages: 337-356, ISSN: 1746-0441- Cite
- Citations: 3
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Journal articleMontuschi P, Adcock IM, 2025,
Protein tyrosine phosphatase 4A3 inhibition: A new pharmacological strategy for acute lung injury?
, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Vol: 392, ISSN: 0022-3565- Cite
- Citations: 1
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Journal articleBloom C, Middleton J, Lewis A, 2025,
Qualitative study of patients experiences and perceptions of stepping down asthma medication in primary care across England
, BMJ Open Respiratory Research, Vol: 12, ISSN: 2052-4439BackgroundGuidelines recommend that asthma medication should be stepped down to the minimally effective dose that achieves symptom control. Stepping down aims to prevent adverse medication effects and unnecessary costs but is often not implemented in primary care, where most asthma patients are managed. Little is known about the experiences and views of patients regarding stepping down. MethodsStable asthma patients, with regular use of a preventer inhaler, from GP practices across England, participated in a survey and/or semi-structured interview. Questions explored the patient’s understanding of their asthma, views and knowledge of preventer inhalers, experiences and perceptions of stepping down asthma medication. Qualitative group-based multi-disciplinary thematic analysis by two healthcare professionals and a patient were performed.Results143 patients responded to the survey, 63% were female, between the ages 18-80 years, and including geographical areas across the UK, 17 of whom participated in an interview. Half of these stable asthma patients, most with asthma for more than 10 years, had never had a discussion regarding stepping down asthma medication. Most stepping down that had occurred was related to seasonal changes in asthma control. Four overarching themes from the interviews were identified, (i) experiences of living with asthma and needing inhalers, (ii) insufficient education regarding preventer inhalers, (ii) stepping down is agreeable and possible and (iv) current asthma care is suboptimal.ConclusionStable asthma patients were able to self-manage their asthma well. They had little awareness of medication adverse effects and minimal experience of having their medication stepped down by a healthcare professional. Most were inclined to step down, if clinically safe to do so, indeed some had reduced their medication doses themselves, without professional guidance.
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Conference paperRathnayake S, Idrees S, Brandsma C, et al., 2025,
IMPACT OF TSLP ON GENE EXPRESSION IN HUMAN AIRWAY EPITHELIAL CELLS
, Publisher: WILEY, Pages: 16-16, ISSN: 1444-0903 -
Conference paperChung L, Thompson B, Siddiqui S, et al., 2025,
INTERPRETING RESPIRATORY OSCILLOMETRY IN ADULTS WITH ASTHMA OR COPD: FINDINGS OF AN INTERNATIONAL DELPHI STUDY
, Publisher: WILEY, Pages: 80-81, ISSN: 1444-0903 -
Journal articleSousa-Pinto B, Costa EM, Vieira RJ, et al., 2025,
Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK-air Study
, CLINICAL AND EXPERIMENTAL ALLERGY, Vol: 55, Pages: 226-238, ISSN: 0954-7894 -
Journal articleLiu M, Yao X, Shi Y, et al., 2025,
Impulse oscillometry-derived equation for prediction of abnormal FEV1/FVC ratio for COPD screening in Chinese population: a multicenter cross-sectional study
, LANCET REGIONAL HEALTH-WESTERN PACIFIC, Vol: 56- Cite
- Citations: 1
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Journal articleLaanesoo A, Mae M, Remm A, et al., 2025,
NLRP1 Is a Prominent Inflammasome Sensor Found in Bronchial Epithelial Cells in Asthma and Can Be Activated by Rhinovirus A16
, CLINICAL AND EXPERIMENTAL ALLERGY, Vol: 55, Pages: 239-246, ISSN: 0954-7894- Cite
- Citations: 1
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Journal articleHopkinson N, 2025,
Chronic obstructive pulmonary disease: new therapies and old needs
, LANCET RESPIRATORY MEDICINE, Vol: 13, Pages: 193-194, ISSN: 2213-2600 -
Journal articleLee HY, Lee Y, Lee S-E, et al., 2025,
Relationships Between Chronic Cough and Asthma Control and Quality of Life in Patients With Severe Asthma: A 6-Month Longitudinal Analysis
, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, Vol: 13, ISSN: 2213-2198- Cite
- Citations: 1
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Journal articleKhaleva E, Brightling C, Eiwegger T, et al., 2025,
Patient-centred composite scores as tools for assessment of response to biological therapy for paediatric and adult severe asthma
, EUROPEAN RESPIRATORY JOURNAL, Vol: 65, ISSN: 0903-1936- Cite
- Citations: 6
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Journal articleKhalaf Z, Saglani S, Bloom CI, 2025,
Implementation and Effectiveness of Guideline-Recommended Clinical Activities for Children With Asthma Population-Based Cohort
, CHEST, Vol: 167, ISSN: 0012-3692 -
Journal articleAgache I, Annesi-Maesano I, Cecchi L, et al., 2025,
EAACI Guidelines on Environmental Science for Allergy and Asthma-Recommendations on the Impact of Indoor Air Pollutants on the Risk of New-Onset Asthma and on Asthma-Related Outcomes
, ALLERGY, ISSN: 0105-4538- Cite
- Citations: 4
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Journal articleDeng R, Wang M, Chung KF, et al., 2025,
Lung proteomic and metabolomic changes induced by carbon black nanoparticles and high humidity in a mouse asthma model
, ENVIRONMENTAL POLLUTION, Vol: 367, ISSN: 0269-7491- Cite
- Citations: 1
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Journal articleHeinemann L, Adcock I, Chung KF, et al., 2025,
Auto-antibodies against carbonyl-modified vimentin in COPD: potential role as a biomarker
, JOURNAL OF INFLAMMATION-LONDON, Vol: 22, ISSN: 1476-9255 -
Journal articleXie Y, Li Y, Su Z, et al., 2025,
Estimating the association between cigarette and e-cigarette use patterns and SARS-CoV-2 negative conversion time: retrospective online survey in China
, BMC INFECTIOUS DISEASES, Vol: 25 -
Journal articleTran HM, Tsai F-J, Wang Y-H, et al., 2025,
Joint effects of temperature and humidity with PM<sub>2.5</sub> on COPD
, BMC PUBLIC HEALTH, Vol: 25- Cite
- Citations: 5
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Journal articlePeltrini R, Cordell RL, Wilde M, et al., 2025,
Discovery and Validation of a Volatile Signature of Eosinophilic Airway Inflammation in Asthma ( vol 210 , pg 1101 , 2024)
, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 211, Pages: 296-296, ISSN: 1073-449X -
Journal articleBloom CI, Yang F, Wedzicha JA, 2025,
Reply to Chung et al. and to Rogliani and Calzetta
, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 211, Pages: 293-294, ISSN: 1073-449X
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