Research Associate in Molecular Virology

Job summary

We are looking for an ambitious and creative Research Associate to join us in a 3 year project funded by the MRC. This position as a Research Associate in Epstein-Barr Virus Molecular Virology will give you the opportunity to investigate novel aspects of the way in which Epstein-Barr Virus causes growth of human cells, relevant to its role in human cancers. Focussing on the EBV EBNA2 and EBNA3 transcription factors, you will use a combination...

Job listing information

  • Reference MED01232
  • Date posted 20 May 2019
  • Closing date 17 June 2019

Job description

Job summary

We are looking for an ambitious and creative Research Associate to join us in a 3 year project funded by the MRC.

This position as a Research Associate in Epstein-Barr Virus Molecular Virology will give you the opportunity to investigate novel aspects of the way in which Epstein-Barr Virus causes growth of human cells, relevant to its role in human cancers. Focussing on the EBV EBNA2 and EBNA3 transcription factors, you will use a combination of molecular and viral genetic approaches to

  • identify and understand novel functional interactions between the EBNA2 and EBNA3 proteins based on their genetic linkage, and
  • define the determinants and significance of functional differences between the main types of EBV strains found in normal infections and human cancers.

The work will be conducted in the laboratory of Dr Rob White and Professor Paul Farrell in the Section of Molecular Virology at Imperial College London. The grant also involves a research collaboration with Professor Michelle West at the University of Sussex.

Duties and responsibilities

Under the guidance of the PI team, you will be responsible for the cloning, modification and production of recombinant EBV strains, and functional assays for EBV infection, such as cell proliferation and differentiation, gene transcription and protein expression. You will contribute intellectually to the progress of the research, also helping with writing of presentations and papers based on this research. You will share some communal duties with other members of the lab and help to support and guide research students, acting as a role model to other members of the lab.

Essential requirements

You will:

  • have a PhD (or be expected to receive one shortly).
  • be an intellectually curious and passionate scientist.
  • have excellent troubleshooting and analytical skills, and attention to detail.
  • have a wide range of molecular biology and/or virology skills.
  • be collegial in your work and attitudes.

It would be an advantage to have expertise in one or more fields complementary to the project, such as:

  • molecular virology
  • molecular oncology
  • molecular or cellular immunology (T and/or B cell biology).

Or you should demonstrate an adaptability that shows potential for excellence in these areas.

Further information

The position is fixed-term for three years from September 2019, with the start date being somewhat flexible for the right candidate.

Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £34,397 - £37,486 per annum.

Should you wish to discuss the project or position in more detail, please contact Rob White (robert.e.white@imperial.ac.uk) or Paul Farrell (p.farrell@imperial.ac.uk).

If you have technical issues with applying, please direct enquiries recruitment@imperial.ac.uk

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level.

http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research

Documents

About Imperial College London

Imperial College London is the UK’s only university focussed entirely on science, engineering, medicine and business and we are consistently rated in the top 10 universities in the world.

You will find our main London campus in South Kensington, with our hospital campuses located nearby in West and North London. We also have Silwood Park in Berkshire and state-of-the-art facilities in development at our major new campus in White City.

We work in a multidisciplinary and diverse community for education, research, translation and commercialisation, harnessing science and innovation to tackle the big global challenges our complex world faces.

It’s our mission to achieve enduring excellence in all that we do for the benefit of society – and we are looking for the most talented people to help us get there.

Additional information

Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.

All Imperial employees are expected to follow the 7 principles of Imperial Expectations: 

  • Champion a positive approach to change and opportunity
  • Communicate regularly and effectively within, and across, teams
  • Consider the thoughts and expectations of others
  • Deliver positive outcomes
  • Encourage inclusive participation and eliminate discrimination
  • Develop and grow skills and expertise
  • Work in a planned and managed way 

In addition to the above, employees are required to observe and comply with all College policies and regulations.

Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.