Research Associate in Molecular Virology
We are looking for an ambitious and creative Research Associate to join us in a 3 year project funded by the MRC. This position as a Research Associate in Epstein-Barr Virus Molecular Virology will give you the opportunity to investigate novel aspects of the way in which Epstein-Barr Virus causes growth of human cells, relevant to its role in human cancers. Focussing on the EBV EBNA2 and EBNA3 transcription factors, you will use a combination...
Job listing information
- Reference MED01232
- Date posted 20 May 2019
- Closing date 17 June 2019
We are looking for an ambitious and creative Research Associate to join us in a 3 year project funded by the MRC.
This position as a Research Associate in Epstein-Barr Virus Molecular Virology will give you the opportunity to investigate novel aspects of the way in which Epstein-Barr Virus causes growth of human cells, relevant to its role in human cancers. Focussing on the EBV EBNA2 and EBNA3 transcription factors, you will use a combination of molecular and viral genetic approaches to
- identify and understand novel functional interactions between the EBNA2 and EBNA3 proteins based on their genetic linkage, and
- define the determinants and significance of functional differences between the main types of EBV strains found in normal infections and human cancers.
The work will be conducted in the laboratory of Dr Rob White and Professor Paul Farrell in the Section of Molecular Virology at Imperial College London. The grant also involves a research collaboration with Professor Michelle West at the University of Sussex.
Duties and responsibilities
Under the guidance of the PI team, you will be responsible for the cloning, modification and production of recombinant EBV strains, and functional assays for EBV infection, such as cell proliferation and differentiation, gene transcription and protein expression. You will contribute intellectually to the progress of the research, also helping with writing of presentations and papers based on this research. You will share some communal duties with other members of the lab and help to support and guide research students, acting as a role model to other members of the lab.
- have a PhD (or be expected to receive one shortly).
- be an intellectually curious and passionate scientist.
- have excellent troubleshooting and analytical skills, and attention to detail.
- have a wide range of molecular biology and/or virology skills.
- be collegial in your work and attitudes.
It would be an advantage to have expertise in one or more fields complementary to the project, such as:
- molecular virology
- molecular oncology
- molecular or cellular immunology (T and/or B cell biology).
Or you should demonstrate an adaptability that shows potential for excellence in these areas.
The position is fixed-term for three years from September 2019, with the start date being somewhat flexible for the right candidate.
Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £34,397 - £37,486 per annum.
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Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.
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