Research Associate

Job summary

We are looking for an outstanding and highly motivated postdoctoral research associate in mass spectrometry – based metabolomics to join the Systems Medicine research group. The group is led by Professor Dumas and works across Imperial College’s and the Department of Metabolism, Digestion and Reproduction (www.imperial.ac.uk/metabolism-digestion-reproduction/) and the National Heart and Lung Institute (www.imperial.ac.uk/nhli). You will...

Job listing information

  • Reference MED02196
  • Date posted 5 January 2021
  • Closing date 7 February 2021

Job description

Job summary

We are looking for an outstanding and highly motivated postdoctoral research associate in mass spectrometry – based metabolomics to join the Systems Medicine research group. The group is led by Professor Dumas and works across Imperial College’s and the Department of Metabolism, Digestion and Reproduction (www.imperial.ac.uk/metabolism-digestion-reproduction/) and the National Heart and Lung Institute (www.imperial.ac.uk/nhli).

You will develop mass spectrometry-based metabolomic workflows (optimisation of chromatographic conditions, maintenance of a comprehensive standards database) and will perform metabolomics studies in human, cellular and animal samples. You will contribute to the identification of host and microbial metabolites and their pathways involved in cardio-metabolism. You will play a role in influencing the project: method development and optimisation, prioritisation of compounds for structural identification, interpretation of results.

You will also have a key role in the recently established Microbiome Network (www.imperial.ac.uk/microbiome-network/) which Professor Dumas is leading and will be required to travel across the various campuses and collaborating institutions to meet the project’s needs.

Duties and responsibilities

You will be in charge of implementing and applying the relevant and innovative methodologies for Mass-Spectrometry-based metabolomics data generated by Prof. Dumas’ group and the Microbiome Network:

  • Management of project data
  • Development of extraction and chromatographic methods for open profiling and targeted quantification in biofluids, tissues and faeces
  • Maintenance of a comprehensive chemical standards database
  • Participation in research meetings and internal seminars
  • Assistance with the administration of the Team and Network as determined by regular meetings
  • Planning and carrying out research in accordance with the project aims
  • Writing progress reports and prepare results for publication and dissemination via presentations at scientific meetings and peer-reviewed journals
  • Presenting research findings to colleagues and at conferences
  • Maintaining accurate and complete records of all findings
  • Assisting with grant applications
  • Liaising as appropriate with international research collaborators/partners
  • Developing contacts and research collaborations within the department/division/faculty and wider academic community in order to further the project aims
  • Promoting the reputation of the group, the department and the College
  • Undertaking appropriate administrative tasks
  • Attending relevant meetings

You may also be asked to carry out teaching duties or to collaborate in other departmental research projects

Essential requirements

You will require to:

  • hold a PhD in Analytical Chemistry or similar with a strong expertise in liquid chromatography coupled to mass spectrometry
  • have a scientific experience in metabolomics (molecules
  • have strong skills in MS data and statistical processing (R, Matlab, Jupiter notebooks), incl. molecular networking and using GNPS to illuminate the dark metabolome

Further information

This is a full time and fixed term contract till the 31st August 2021.

Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £36,045 - £39,183 per annum.

Should you require any further details on the role please contact: Prof. Marc-Emmanuel Dumas  – m.dumas@imperial.ac.uk .

For technical issues when applying online please email recruitment@imperial.ac.uk

 

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level.

http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research

Documents

About Imperial College London

Imperial College London is the UK’s only university focussed entirely on science, engineering, medicine and business and we are consistently rated in the top 10 universities in the world.

You will find our main London campus in South Kensington, with our hospital campuses located nearby in West and North London. We also have Silwood Park in Berkshire and state-of-the-art facilities in development at our major new campus in White City.

We work in a multidisciplinary and diverse community for education, research, translation and commercialisation, harnessing science and innovation to tackle the big global challenges our complex world faces.

It’s our mission to achieve enduring excellence in all that we do for the benefit of society – and we are looking for the most talented people to help us get there.

Additional information

Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.

All Imperial employees are expected to follow the 7 principles of Imperial Expectations: 

  • Champion a positive approach to change and opportunity
  • Communicate regularly and effectively within, and across, teams
  • Consider the thoughts and expectations of others
  • Deliver positive outcomes
  • Encourage inclusive participation and eliminate discrimination
  • Develop and grow skills and expertise
  • Work in a planned and managed way 

In addition to the above, employees are required to observe and comply with all College policies and regulations.

Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.