The Lloyd Lab consists of a multidisciplinary group of immunologists, cell biologists and clinical academics who aim to understand the molecular mechanisms underlying common lung diseases, including asthma and fibrotic lung diseases. We utilise mouse models, and in vitro culture systems, using cells from patients, to investigate the mechanisms underlying the pulmonary immune response to inhaled particles, allergens and pathogens. Broadly our...
Job listing information
- Reference MED02200
- Date posted 11 January 2021
- Closing date 10 February 2021
The Lloyd Lab consists of a multidisciplinary group of immunologists, cell biologists and clinical academics who aim to understand the molecular mechanisms underlying common lung diseases, including asthma and fibrotic lung diseases. We utilise mouse models, and in vitro culture systems, using cells from patients, to investigate the mechanisms underlying the pulmonary immune response to inhaled particles, allergens and pathogens. Broadly our research encompasses three areas: 1) Immune regulation in the lung, 2) development of pulmonary immunity in early life and 3) mechanisms underlying lung repair versus remodelling.
This post has been created as part of a multidisciplinary project funded by the Wellcome Trust to investigate the neuro-immune-stromal interactions in response to environmental change and how this drives allergic airway inflammation and remodelling. This grant will combine well established mouse models developed in the lab together with machine learning tools and imaging techniques to understand the mechanisms underlying tissue remodelling versus repair during severe asthma.
Duties and responsibilities
Under the direction of the line manager you will:
- Be responsible for immunisations, genotyping transgenic colonies, measurement of lung function, sampling of the airways, tissue preparation and RNA and DNA preparation.
- Conduct cytokine assays, histological analysis, immunocytochemistry, in situ hybridisation, flow cytometry, in vitro culture of leukocytes and lung structural cells
- Assist other members of the lab with their in vivo experiments
- Have experience of some or all of these techniques would be advantageous, but training is also available
- General laboratory administrative duties including ordering when needed
- Maintaining stock of routine supplies
- Documentation and analysis of experimental data
- Participation in local laboratory meetings
- Ensuring good laboratory practice is in place
- Assist with presentation of results to the group, collaborators, and to the research community in general
- Assist with preparation of grant reports and scientific publications
- To help maintain a highly efficient working laboratory
- To undertake any necessary training as required
You should have:
- BSc in basic biological sciences or equivalent vocational qualification
- Have at least 2 years experience in laboratory-based research
- Home Office Personal Licence
- Practical experience with in vivo mouse models
This is a full time, fixed term contract for 2 years
You will be required to complete an online application for this post.
Should you require any further details on the role please contact: Laura Yates, Research Manager Lloyd Lab - firstname.lastname@example.org.
For technical issues when applying online please email email@example.com
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