Research Technician

Job summary

The Lloyd Lab consists of a multidisciplinary group of immunologists, cell biologists and clinical academics who aim to understand the molecular mechanisms underlying common lung diseases, including asthma and fibrotic lung diseases. We utilise mouse models, and in vitro culture systems, using cells from patients, to investigate the mechanisms underlying the pulmonary immune response to inhaled particles, allergens and pathogens. Broadly our...

Job listing information

  • Reference MED02200
  • Date posted 11 January 2021
  • Closing date 10 February 2021

Job description

Job summary

The Lloyd Lab consists of a multidisciplinary group of immunologists, cell biologists and clinical academics who aim to understand the molecular mechanisms underlying common lung diseases, including asthma and fibrotic lung diseases. We utilise mouse models, and in vitro culture systems, using cells from patients, to investigate the mechanisms underlying the pulmonary immune response to inhaled particles, allergens and pathogens. Broadly our research encompasses three areas: 1) Immune regulation in the lung, 2) development of pulmonary immunity in early life and 3) mechanisms underlying lung repair versus remodelling.

This post has been created as part of a multidisciplinary project funded by the Wellcome Trust to investigate the neuro-immune-stromal interactions in response to environmental change and how this drives allergic airway inflammation and remodelling. This grant will combine well established mouse models developed in the lab together with machine learning tools and imaging techniques to understand the mechanisms underlying tissue remodelling versus repair during severe asthma.

Duties and responsibilities

Under the direction of the line manager you will:

  • Be responsible for immunisations, genotyping transgenic colonies, measurement of lung function, sampling of the airways, tissue preparation and RNA and DNA preparation.
  • Conduct cytokine assays, histological analysis, immunocytochemistry, in situ hybridisation, flow cytometry, in vitro culture of leukocytes and lung structural cells
  • Assist other members of the lab with their in vivo experiments
  • Have experience of some or all of these techniques would be advantageous, but training is also available
  • General laboratory administrative duties including ordering when needed
  • Maintaining stock of routine supplies
  • Documentation and analysis of experimental data
  • Participation in local laboratory meetings
  • Ensuring good laboratory practice is in place
  • Assist with presentation of results to the group, collaborators, and to the research community in general
  • Assist with preparation of grant reports and scientific publications
  • To help maintain a highly efficient working laboratory
  • To undertake any necessary training as required

Essential requirements

You should have:

  • BSc in basic biological sciences or equivalent vocational qualification
  • Have at least 2 years experience in laboratory-based research
  • Home Office Personal Licence
  • Practical experience with in vivo mouse models

Further information

This is a full time, fixed term contract for 2 years 

You will be required to complete an online application for this post.

Should you require any further details on the role please contact: Laura Yates, Research Manager Lloyd Lab -  l.yates@imperial.ac.uk.

For technical issues when applying online please email recruitment@imperial.ac.uk

 

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level.

http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research

Documents

About Imperial College London

Imperial College London is the UK’s only university focussed entirely on science, engineering, medicine and business and we are consistently rated in the top 10 universities in the world.

You will find our main London campus in South Kensington, with our hospital campuses located nearby in West and North London. We also have Silwood Park in Berkshire and state-of-the-art facilities in development at our major new campus in White City.

We work in a multidisciplinary and diverse community for education, research, translation and commercialisation, harnessing science and innovation to tackle the big global challenges our complex world faces.

It’s our mission to achieve enduring excellence in all that we do for the benefit of society – and we are looking for the most talented people to help us get there.

Additional information

Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.

All Imperial employees are expected to follow the 7 principles of Imperial Expectations: 

  • Champion a positive approach to change and opportunity
  • Communicate regularly and effectively within, and across, teams
  • Consider the thoughts and expectations of others
  • Deliver positive outcomes
  • Encourage inclusive participation and eliminate discrimination
  • Develop and grow skills and expertise
  • Work in a planned and managed way 

In addition to the above, employees are required to observe and comply with all College policies and regulations.

Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.