The Lloyd lab, funded by the Wellcome Trust, has embarked on a multidisciplinary project to investigate neuro-immune-stromal interactions in response to environmental change, and how this drives allergic airway inflammation and remodelling. We use patient samples and neonatal/adult allergic airway mouse models to determine immune-neuro interactions and assess their impact on disease progression, pathology, and lung function...
Job listing information
- Reference MED03283
- Date posted 11 November 2022
- Closing date 9 December 2022
The Lloyd lab, funded by the Wellcome Trust, has embarked on a multidisciplinary project to investigate neuro-immune-stromal interactions in response to environmental change, and how this drives allergic airway inflammation and remodelling.
We use patient samples and neonatal/adult allergic airway mouse models to determine immune-neuro interactions and assess their impact on disease progression, pathology, and lung function (www.lloydlab.co.uk)
To fully comprehend the complex interactions between the different cellular compartments in lungs, we are looking for an individual to develop and drive the integration of advanced imaging technologies and spatial transcriptomics. Data analysis will be a key component of this project and therefore a keen interest in mining complex data sets will be essential.
Duties and responsibilities
- Actively participate in the research programme of the Lloyd Group
- Conduct and plan own scientific work
- Identify and develop techniques, software, equipment for the collection and analysis of data
- Assist in the supervision of students and research assistants
- To publish in high quality journals and to present data at national and international meetings
The successful candidate will have a PhD in a related discipline, and be technically proficient in a range of laboratory skills, have the ambition and drive to succeed.
Research Associate: Hold a PhD in Immunology or a closely related discipline.
Research Assistant: Near completion of a PhD in Immunology or a closely related discipline.
*Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant.
- Extensive Microscopy experience (Confocal, widefield, live cell imaging, intravital or IMC). Knowledge or experience of Second Harmonic Generation microscopy would be advantageous.
- Image Analysis and associated software including Image J, ICY, IMARIS, Huygens, Volocity, MCD, Cell Profiler, ilastik.
- Experience of single cell or bulk RNAseq, NGS, Spatial Transcriptomics or proteomics would be advantageous as would experience using R and/or python code for bioinformatics data analysis of multiplex datasets. Knowledge of MATLAB, Perl, CellPhoneDB, CellChat, NicheNet, Seurat.
- In vivo experience, preferably with a home office license - PIL A,B and C.
This post will provide the opportunity to develop and drive a research project as well as writing up work for presentation and publication. Therefore, the ability to work independently and as part of a team, have excellent communication, organisational and problem-solving skills are essential.
This is a full time and fixed term post until July 2026. You will be based at the South Kensington Campus.
Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £38,194 - £41,388 per annum.
Should you require any further details on the role please contact: Laura Yates, Research Manager Lloyd Lab - email@example.com.
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