Research Associate in Molecular Biology

Job summary

The Department of Life Sciences was the top ranked university department in the UK for research intensity in Biological Sciences in REF2014 (Times Higher Education), scoring 100% on our environment. We are seeking to appoint a Research Associate to join a world-leading and dynamic research team at the Department of Life Sciences at Imperial College London, South Kensington Campus. Successful applicants will help produce independent and...

Job listing information

  • Reference NAT00322
  • Date posted 16 November 2018
  • Closing date 20 December 2018

Job description

Job summary

The Department of Life Sciences was the top ranked university department in the UK for research intensity in Biological Sciences in REF2014 (Times Higher Education), scoring 100% on our environment.

We are seeking to appoint a Research Associate to join a world-leading and dynamic research team at the Department of Life Sciences at Imperial College London, South Kensington Campus. Successful applicants will help produce independent and original research within part of a large team of postdocs and technicians within the Crisanti group at Imperial College that forms part of a larger, multi-disciplinary research consortium called Target Malaria. The Crisanti lab has pioneered the genetic transformation of the human malaria mosquito and it is now focused on projects aimed at creating gene drive systems based on the use of DNA endonucleases with the ultimate goal of malaria control by decreasing the reproductive potential of mosquito populations. The lab has achieved a number of notable successes in recent years and is at the frontier in the field of mosquito transgenesis, genome editing and gene drive.

An important, unique aspect of this role will be to provide molecular biology and genetics training to more junior members of a large laboratory, to assist in their professional development and to ensure the highest research standards are maintained in the laboratory.

The project is aimed at designing, building, and testing novel gene drives through the incorporation of three components: nucleases with improved activity; rational choice of new genetic targets to be affected by the gene drive; modulating and regulating gene drive expression in time and space

Duties and responsibilities


  • Taking initiatives in the planning of research

  • Directing the work of small research teams including undergraduate and postgraduate students

  • Identifying and developing suitable techniques, and apparatus, for the collection and analysis of data

  • Conducting data analysis and ensuring the validity and reliability of data at all times

  • Maintaining accurate and complete records of all findings

  • Writing regular (monthly) internal reports

Essential requirements


  • A PhD (or equivalent) in Biological Sciences or a related subject with a strong background in and understanding of molecular and cellular biology and genetics, evidenced by contributions to publications.


You must be able to demonstrate:



  • experience in genome editing

  • significant experience in molecular biology including modern methods of DNA cloning
    experience in the use of DNA analysis software (Vector NTI, Geneious, Benchling or similar)

  • significant experience in genetic techniques

  • proven experience in teaching laboratory techniques

  • experience of day to day supervision of masters and/or PhD students

  • experience of working with model organisms

  • demonstrable knowledge of the most up to date techniques in molecular biology such as electrophoresis, PCR, qPCR, molecule blotting and probing, site specific mutagenesis, bacteria and cell–lines transformations.

  • knowledge of genetics


You must also be able to demonstrate:



  • the ability to work effectively as part of a team and to be open minded and cooperative.

  • the ability to develop and apply new concepts and have a creative approach to problem-solving.

  • excellent verbal and written communication skills, and be able to write clearly and succinctly for publication.

  • the ability to organise your own work with minimal supervision, and prioritise effectively in response to deadlines.

Further information

*Candidates who have not yet been officially awarded their PhD, will be appointed as a Research Assistant within the salary range £33,380 - £35,061 per annum.

This is a full-time, fixed-term positions available until 31 January 2020, with the possibility of extension subject to the availability of funding.

For informal enquiries please contact Professor Andrea Crisanti (via l.collyns@imperial.ac.uk)

Queries relating to the application process should be directed to Peggy Baker, Senior HR Administrator, at peggy.baker@imperial.ac.uk.

For technical queries when applying online, please contact recruitment@imperial.ac.uk

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level.http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research

 

Documents

About Imperial College London

Imperial College London is the UK’s only university focussed entirely on science, engineering, medicine and business and we are consistently rated in the top 10 universities in the world.

You will find our main London campus in South Kensington, with our hospital campuses located nearby in West and North London. We also have Silwood Park in Berkshire and state-of-the-art facilities in development at our major new campus in White City.

We work in a multidisciplinary and diverse community for education, research, translation and commercialisation, harnessing science and innovation to tackle the big global challenges our complex world faces.

It’s our mission to achieve enduring excellence in all that we do for the benefit of society – and we are looking for the most talented people to help us get there.

Additional information

Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.

All Imperial employees are expected to follow the 7 principles of Imperial Expectations: 

  • Champion a positive approach to change and opportunity
  • Communicate regularly and effectively within, and across, teams
  • Consider the thoughts and expectations of others
  • Deliver positive outcomes
  • Encourage inclusive participation and eliminate discrimination
  • Develop and grow skills and expertise
  • Work in a planned and managed way 

In addition to the above, employees are required to observe and comply with all College policies and regulations.

Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.