Bioinformatician: Phyre Software Developer

Job summary

We are looking to recruit a bioinformatician to develop and disseminate our widely-used protein modelling portal Phyre2. Phyre2 (www.sbg.bio.ic.ac.uk/~phyre2 ) is used internationally with over 90,000 distinct users each year. This will be a post for up to 3 years as part of a collaboration between Professor Mike Sternberg’s group at Imperial and the University of Kansas, USA and is funded by a BBSRC-NSF grant.  

Job listing information

  • Reference NAT00571
  • Date posted 28 November 2019
  • Closing date 2 January 2020

Job description

Job summary

We are looking to recruit a bioinformatician to develop and disseminate our widely-used protein modelling portal Phyre2. Phyre2 (www.sbg.bio.ic.ac.uk/~phyre2 ) is used internationally with over 90,000 distinct users each year. This will be a post for up to 3 years as part of a collaboration between Professor Mike Sternberg’s group at Imperial and the University of Kansas, USA and is funded by a BBSRC-NSF grant.  

Duties and responsibilities


  • To develop and support the Phyre protein structure prediction server working on both the algorithmic back-end and the web front-end

  • To map missense variants onto predicted protein structures

  • To collaborate with the team at Kansas in the development of the related resource GWYRE

  • To disseminate to the community Phyre and GWYRE via publications, conference presentations and workshops


 

Essential requirements

In outline, you must have:

  • A degree (undergraduate or postgraduate) focused on a computationally-based topic or an equivalent qualification or experience
  • Extensive experience of coding to a professional level in a high-level language (ideally Python, Perl, Java or a C language)
  • Experience of computational development of algorithms to a professional level ideally on protein modelling

The following are also highly desirable requirements:

  • Understanding of the three-dimensional structure of biological molecules especially proteins
  • Experience of the Linux operating system
  • A publication records appropriate for your previous career of papers in computational biology / bioinformatics involving software development
  • Experience of development of a dynamic web site

Further information

This is full time fixed term position for up to 33 months. Appointments will usually be made at the bottom of the Professional Services Level 4 scale.

To be considered candidates are required to apply online and fill out the online application.

For informal enquiries on the role please contact: Prof Michael Sternberg m.sternberg@imperial.ac.uk

For technical issues when applying online, please contact: recruitment@imperial.ac.uk

Documents

About Imperial College London

Imperial College London is the UK’s only university focussed entirely on science, engineering, medicine and business and we are consistently rated in the top 10 universities in the world.

You will find our main London campus in South Kensington, with our hospital campuses located nearby in West and North London. We also have Silwood Park in Berkshire and state-of-the-art facilities in development at our major new campus in White City.

We work in a multidisciplinary and diverse community for education, research, translation and commercialisation, harnessing science and innovation to tackle the big global challenges our complex world faces.

It’s our mission to achieve enduring excellence in all that we do for the benefit of society – and we are looking for the most talented people to help us get there.

Additional information

Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.

All Imperial employees are expected to follow the 7 principles of Imperial Expectations: 

  • Champion a positive approach to change and opportunity
  • Communicate regularly and effectively within, and across, teams
  • Consider the thoughts and expectations of others
  • Deliver positive outcomes
  • Encourage inclusive participation and eliminate discrimination
  • Develop and grow skills and expertise
  • Work in a planned and managed way 

In addition to the above, employees are required to observe and comply with all College policies and regulations.

Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.