Research Associate

Job summary

The Department of Life Sciences was the top ranked university department in the UK for research intensity in Biological Sciences in REF2014 (Times Higher Education), scoring 100% on our environment.   Applications are invited for a Research Associate to join a group studying the biochemistry and cell biology of glycan-binding receptors, under the direction of Professor Kurt Drickamer and Dr Maureen Taylor at Imperial College’s South...

Job listing information

  • Reference NAT00959
  • Date posted 7 July 2021
  • Closing date 4 August 2021

Job description

Job summary

The Department of Life Sciences was the top ranked university department in the UK for research intensity in Biological Sciences in REF2014 (Times Higher Education), scoring 100% on our environment.

 

Applications are invited for a Research Associate to join a group studying the biochemistry and cell biology of glycan-binding receptors, under the direction of Professor Kurt Drickamer and Dr Maureen Taylor at Imperial College’s South Kensington Campus. The aim of this project is to develop a human lectin array for sreening interactions of microbial pathogens with the innate immune system. The approach used will be to clone and express fragments of human glycan-binding receptors, use biotin tags to immobilise these in various array formats, test the arrays for binding of bacteria and viruses relevant to infections, and develop an online database for presentation of the results. Follow-up experiments will be aimed at identifying sugar ligands for the receptors.

Duties and responsibilities

Your key responsibilities will involve day-to-day running of the project, including expressing and characterizing sugar-binding domains from receptors, labelling of bacterial and viral samples, and performing array screening. Follow-up experiments will encompass solid phase binding studies and preparing proteins for structural analysis. You will also be responsible for updating and maintaining the database of glycan-binding proteins in animal systems and assisting in preparation of manuscripts for publication.

Essential requirements


  • Research Associate: PhD (or equivalent) in biochemistry or a related scientific discipline

  • Research Assistant: Near completion of a PhD (or equivalent) in biochemistry or a related scientific discipline


Experience in protein expression, purification and characterization as well as molecular biology techniques for development of expression systems are essential. Experience with cell culture would be desirable. Familiarity with use of computer programs such as Excel for data analysis is essential, and experience with web site management would be an advantage.


You must also have knowledge of biochemistry, including specific knowledge in the field of protein structure and function analysis, as well as molecular biology, including cloning, mutagenesis and DNA sequencing. A record of publications in biochemical study of proteins is desirable.


You must have excellent verbal and written communication skills and be able to write clearly and succinctly for publication. You must have a creative approach to problem-solving, the ability to develop and apply new concepts, prioritise your work in response to deadlines and be able to work as part of a team, as well as independently. You must also be able to relate well to others and form positive relationships with a wide range of people and work with researchers from different scientific backgrounds. 

Further information

This is a full-time, fixed term position available for up to 36 months based at the South Kensington Campus.

*Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant within the salary range £36,045 - £39,183 per annum. 

Should you have any informal queries please contact:

Professor Kurt Drickamer (k.drickamer@imperial.ac.uk) and Dr Maureen Taylor (maureen.taylor@imperial.ac.uk).

 

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level. http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research

We are committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment for all. We therefore encourage candidates to apply irrespective of age, disability, marriage or civil partnership status, pregnancy or maternity, race, religion and belief, gender identity, sex, or sexual orientation. We are an Athena SWAN Silver Award winner, a Disability Confident Leader and a Stonewall Diversity Champion.

Documents

About Imperial College London

Imperial College London is the UK’s only university focussed entirely on science, engineering, medicine and business and we are consistently rated in the top 10 universities in the world.

You will find our main London campus in South Kensington, with our hospital campuses located nearby in West and North London. We also have Silwood Park in Berkshire and state-of-the-art facilities in development at our major new campus in White City.

We work in a multidisciplinary and diverse community for education, research, translation and commercialisation, harnessing science and innovation to tackle the big global challenges our complex world faces.

It’s our mission to achieve enduring excellence in all that we do for the benefit of society – and we are looking for the most talented people to help us get there.

Additional information

Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.

All Imperial employees are expected to follow the 7 principles of Imperial Expectations: 

  • Champion a positive approach to change and opportunity
  • Communicate regularly and effectively within, and across, teams
  • Consider the thoughts and expectations of others
  • Deliver positive outcomes
  • Encourage inclusive participation and eliminate discrimination
  • Develop and grow skills and expertise
  • Work in a planned and managed way 

In addition to the above, employees are required to observe and comply with all College policies and regulations.

We are committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment for all. We therefore encourage candidates to apply irrespective of age, disability, marriage or civil partnership status, pregnancy or maternity, race, religion and belief, gender identity, sex, or sexual orientation. We are an Athena SWAN Silver Award winner, a Disability Confident Leader and a Stonewall Diversity Champion.

For technical issues when applying online please email support.jobs@imperial.ac.uk.