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  • Book chapter
    Nash RDM, Geffen AJ, 2005,

    Age and growth

    , FLATFISHES: BIOLOGY AND EXPLOITATION, Editors: Gibson, Publisher: BLACKWELL SCIENCE PUBL, Pages: 138-163
  • Journal article
    Morales-Nin B, Swan SC, Gordon JDM, Palmer M, Geffen AJ, Shimmield T, Sawyer Tet al., 2005,

    Age-related trends in otolith chemistry of <i>Merluccius merluccius</i> from the north-eastern Atlantic Ocean and the western Mediterranean Sea

    , MARINE AND FRESHWATER RESEARCH, Vol: 56, Pages: 599-607, ISSN: 1323-1650
  • Conference paper
    Purvis A, Cardillo M, Grenyer R, Collen Bet al., 2005,

    Correlates of extinction risk: phylogeny, biology, threat and scale

    , Symposium of the Zoological-Society-of-London, Publisher: CAMBRIDGE UNIV PRESS, Pages: 295-316, ISSN: 1363-3090
  • Journal article
    Pazos F, Ranea JAG, Juan D, Sternberg MJEet al., 2005,

    Assessing protein co-evolution in the context of the tree of life assists in the prediction of the interactome

    , J MOL BIOL, Vol: 352, Pages: 1002-1015, ISSN: 0022-2836
  • Journal article
    Christophides G, Meister S, Koutsos A, Blass C, Kanzok S, Vlachou D, Schlegelmilch T, Osta M, Zheng L, Kafatos Fet al., 2005,

    Systems biology of the <i>Anopheles gainbiae</i> innate immunity [MIM-GC-22590]

    , ACTA TROPICA, Vol: 95, Pages: S44-S45, ISSN: 0001-706X
  • Journal article
    Ewers RM, 2005,

    In search of the rain forest

    , Environmental Conservation, Vol: 32, Pages: 190-191
  • Journal article
    Madhusudan S, Smart F, Shrimpton P, Parsons JL, Gardiner L, Houlbrook S, Talbot DC, Hammonds T, Freemont PA, Sternberg MJE, Dianov GL, Hickson IDet al., 2005,

    Isolation of a small molecule inhibitor of DNA base excision repair

    , NUCLEIC ACIDS RESEARCH, Vol: 33, Pages: 4711-4724, ISSN: 0305-1048
  • Journal article
    Ewers RM, 2005,

    Are conservation and development compatable?

    , Trends in Ecology and Evolution, Vol: 20, Pages: 159-159
  • Journal article
    Bacarese-Hamilton T, Gray J, Ardizzoni A, Crisanti Aet al., 2005,

    Allergen microarrays.

    , Methods Mol Med, Vol: 114, Pages: 195-207, ISSN: 1543-1894

    Allergy affects more than 25% of Western populations (1) and is estimated to be the sixth leading cause of chronic disease in the United States and Western Europe. The complexity of the condition is such that hundreds of common allergens have been described, and in order to maximize diagnostic efficiency there is an urgent clinical requirement for assays to provide multiple-allergen determination in a timely and cost-effective manner. Miniaturized immunoassays that utilize protein microarray technology now offer the possibility of circumventing most of the current limitations in the serodiagnosis of allergic disease. The heterogeneous nature of allergens presents many challenges in all aspects of developing such arrays, from immobilization of the capture molecule to detection of the bound ligand. In addition, there is no simple method of protein amplification (such as PCR for nucleic acids), and stabilization is yet a further major consideration. Notwithstanding these challenges, protein microarrays have been developed for the serodiagnosis of allergies and other complex clinical conditions. These assays exhibit good analytical and clinical performance and deliver significant advantages in convenience and cost compared with traditional ELISA test formats. This chapter details the techniques employed in the construction and processing of an allergen array specific for the serodiagnosis of allergic disease. An overview of protein microarray technology is provided and the principles that underpin the suitability for use of this technology in the identification and measurement of particular proteins in patient sera (serum profiling) are discussed.
  • Conference paper
    Savolainen V, Forest F, 2005,

    Species-level phylogenetics from continental biodiversity hotspots

    , Conference on Plant Species-level Systematics, Publisher: A R G GANTNER VERLAG K G, Pages: 17-30, ISSN: 0080-0694
  • Conference paper
    Barraclough TG, Davies TJ, 2005,

    Predicting future speciation

    , Symposium of the Zoological-Society-of-London, Publisher: CAMBRIDGE UNIV PRESS, Pages: 400-418, ISSN: 1363-3090
  • Conference paper
    Purvis A, Gittleman JL, Brooks TM, 2005,

    Phylogeny and conservation

    , Symposium of the Zoological-Society-of-London, Publisher: CAMBRIDGE UNIV PRESS, Pages: 1-16, ISSN: 1363-3090
  • Book chapter
    Matthews S, 2005,

    NMR of proteins and nucleic acids

    , RSc Special Periodical Reports, Editors: Webb, Pages: 355-390
  • Journal article
    Wigneshweplaraj SR, Burrows PC, Bordes P, Schumacher J, Rappas M, Finn RD, Cannon WV, Zhang X, Buck Met al., 2005,

    The second paradigm for activation of transcription

    , PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 79, Vol: 79, Pages: 339-369, ISSN: 0079-6603
  • Journal article
    Ewers RM, Cowley G, 2005,

    The role of sound production in determining dominance in agonistic interactions between male tree wetas (Hemideina crassidens, Orthoptera: Anostostomatidae)

    , New Zealand Natural Sciences, Vol: 30, Pages: 11-17
  • Book
    Turnbull CGN ed, 2005,

    Plant architecture and its manipulation

    , UK, Publisher: Blackwell, ISBN: 9781405121286
  • Conference paper
    Wigneshweraraj SR, Burrows PC, Bordes P, Schumacher J, Rappas M, Finn RD, Cannon WV, Zhang X, Buck Met al., 2005,

    The structural basis for <i>nif</i> gene activation

    , 14th International Nitrogen Fixation Congress, Publisher: SPRINGER, Pages: 59-63, ISSN: 0924-1949
  • Book chapter
    P J Nixon, M Sarcina, B A Diner, 2005,

    The D1 and D2 core subunits

    , Photosystem II: The Light-Driven Water:Plastoquinone Oxidoreductase, Editors: Wydrzynski, Satoh, Dordrecht, The Netherlands, Publisher: Kluwer Academic Publishers, Pages: 71-94
  • Conference paper
    Clark GF, Khoo KH, Wong NK, Sutton-Smith M, Patankar MS, Lattanzio FA, Morris HR, Dell Aet al., 2005,

    Analysis of protein glycosylation in a sperm-somatic cell adhesion system.

    , 38th Annual Meeting of the Society-for-the-Study-of-Reproduction, Publisher: SOC STUDY REPRODUCTION, Pages: 155-156, ISSN: 0006-3363
  • Conference paper
    Purvis A, Orme CDL, 2005,

    Evolutionary trends in body size

    , Berlin, Publisher: Springer-Verlag, Pages: 1-18
  • Book chapter
    Endres RG, 2005,

    Inner-sphere reorganization energies of outer-sphere self-exchange reactions utilizing density functional theory

    , Trends in chemical physics research, Editors: Linke, New York, Publisher: Nova Science, ISBN: 1-59454-483-2
  • Book chapter
    Martin I Bidartondo, Monique Gardes, 2005,

    Fungal diversity in molecular terms: profiling, identification, and quantification in the environment.

    , The Fungal Community, Editors: Dighton J, White JF, Oudemans PV, Boca Raton, Florida, Publisher: CRC Press, Taylor & Francis Group, Pages: 215-239, ISBN: 9780824723552
  • Conference paper
    Muggleton S, Lodhi H, Amini A, Sternberg MJEet al., 2005,

    Support vector inductive logic programming

    , Berlin, 8th International Conference on Discovery Science, 8 - 11 October 2005, Singapore, SINGAPORE, Publisher: Springer-Verlag, Pages: 163-175
  • Book
    Belgrano A, Woodward G, 2005,

    Aquatic Food Webs

    , Publisher: Oxford University Press, ISBN: 9780198564829
  • Journal article
    Lloyd LJ, Jones SE, Jovanovic G, Gyaneshwar P, Rolfe MD, Thompson A, Hinton JC, Buck Met al., 2004,

    Identification of a new member of the phage shock protein response in <i>Escherichia coli</i>, the phage shock protein g (PspG)

    , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 279, Pages: 55707-55714, ISSN: 0021-9258
  • Journal article
    Kennis JTM, Larsen DS, van Stokkum IHM, Vengris M, van Thor JJ, van Grondelle Ret al., 2004,

    Uncovering the hidden ground state of green fluorescent protein

    , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 101, Pages: 17988-17993, ISSN: 0027-8424
  • Journal article
    Kirilovsky D, Roncel M, Boussac A, Wilson A, Zurita JL, Ducruet JM, Bottin H, Sugiura M, Ortega JM, Rutherford AWet al., 2004,

    Cytochrome <i>c</i><sub>550</sub> in the cyanobacterium <i>Thermosynechococcus elongatus</i> -: Study of redox mutants

    , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 279, Pages: 52869-52880, ISSN: 0021-9258
  • Journal article
    Ouhammouch M, Werner F, Weinzierl ROJ, Geiduschek EPet al., 2004,

    A fully recombinant system for activator-dependent archaeal transcription

    , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 279, Pages: 51719-51721, ISSN: 0021-9258
  • Journal article
    Brunkhorst A, Neuman T, Hall A, Arenas E, Bartfai T, Hermanson O, Metsis Met al., 2004,

    Novel isoforms of the TFIID subunit TAF4 modulate nuclear receptor-mediated transcriptional activity.

    , Biochem Biophys Res Commun, Vol: 325, Pages: 574-579, ISSN: 0006-291X

    The transcription factor TFIID consists of TATA-binding protein (TBP) and TBP-associated factors (TAFs). TAFs are essential for modulation of transcriptional activity but the regulation of TAFs is complex and many important aspects remain unclear. In this study, we have identified and characterized five novel truncated forms of the TFIID subunit TAF4 (TAF(II)135). Analysis of the mouse gene structure revealed that all truncations were the results of alternative splicing and resulted in the loss of domains or parts of domains implicated in TAF4 functional interactions. Results from transcriptional assays showed that several of the TAF4 isoforms exerted dominant negative effects on TAF4 activity in nuclear receptor-mediated transcriptional activation. In addition, alternative TAF4 isoforms could be detected in specific cell types. Our results indicate an additional level of complexity in TAF4-mediated regulation of transcription and suggest context-specific roles for these new TAF4 isoforms in transcriptional regulation in vivo.
  • Journal article
    Dunsby C, Lanigan PMP, McGinty J, Elson DS, Requejo-Isidro J, Munro I, Galletly N, McCann F, Treanor B, Önfelt B, Davis DM, Neil MAA, French PMWet al., 2004,

    An electronically tunable ultrafast laser source applied to fluorescence imaging and fluorescence lifetime imaging microscopy

    , JOURNAL OF PHYSICS D-APPLIED PHYSICS, Vol: 37, Pages: 3296-3303, ISSN: 0022-3727

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