Pharmacology and Therapeutics
Research within this theme will produce novel antimicrobial therapeutics which will replace treatments to which resistance is widespread in clinical practice. This theme brings together expertise in antimicrobial synthesis and drug design towards novel targets, target validation, the efficacy of target protein inhibition, and analysis of the effects on bacterial cells. Our researchers are devising parallel synthesis of compounds to provide hit structures for bioassay and optimisation of structure-activity relationships to provide lead compounds for further in vivo studies. These lead compounds will eventually progress into phase-I clinical trials.
Members of the pharmacology and therapeutics theme
Professor Alan Armstrong
![Professor Alan Armstrong](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Armstrong,-Alan--tojpeg_1471534405141_x4.jpg)
Professor Alan Armstrong
Head of Department of Chemistry
Dr Anna Barnard
![dr anna barnard](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/barnard-anna-2-tojpeg-1525453044172-x1_1603372449187_x4.jpg)
Dr Anna Barnard
Research Fellow (Sir Henry Dale Fellowship)
Professor Anthony Barrett
![Professor Anthony Barrett](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Barrett,-Anthony--tojpeg_1471534500411_x4.jpg)
Professor Anthony Barrett
Head of Synthesis
Dr Rongjun Chen
![Dr Rongjun Chen](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/rongjun-chen--tojpeg_1579774448602_x4.jpg)
Dr Rongjun Chen
Reader in Biomaterials Engineering
Dr Matthew Child
![Dr Matthew Child](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/01--tojpeg_1501847256421_x4.jpg)
Dr Matthew Child
Research Fellow (Sir Henry Dale Fellow)
Dr Ceire Costelloe
![Dr Ceire Costelloe](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Costelloe,-Ceire--tojpeg_1471250571840_x4-1.jpg)
Dr Ceire Costelloe
Career Development Fellow
Dr Tom Ellis
![Dr Tom Ellis](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Ellis,-Tom--tojpeg_1471534571767_x4.jpg)
Dr Tom Ellis
Senior Lecturer in Synthetic Biology
Dr Lindsay Evans
![Dr Lindsay Evans](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Evans,-Lindsay--tojpeg_1471534668187_x4.jpg)
Dr Lindsay Evans
Research Associate
Dr Matthew Fuchter
![Dr Matthew Fuchter](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Fuchter,-Matthew--tojpeg_1471534735986_x4.jpg)
Dr Matthew Fuchter
Reader in Chemistry
Dr John Heap
![Dr John Heap](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/01--tojpeg_1501579994560_x4.jpg)
Dr John Heap
Lecturer in Synthetic Biology
Dr Julie McDonald
![Dr Julie McDonald](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Julie-McDonald-JPG--tojpeg_1573720788301_x4.jpg)
Dr Julie McDonald
Research Associate (Metabonomics & Microbiomics)
Professor Alan Spivey
![Professor Alan Spivey](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Spivey,-Alan--tojpeg_1471534805663_x4.jpg)
Professor Alan Spivey
Professor of Synthetic Chemistry
Professor Ed Tate
![Professor Ed Tate](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Tate,-Ed--tojpeg_1471534886229_x4.jpg)
Professor Ed Tate
Professor of Chemical Biology
Professor Martin Wilkins
![Professor Martin Wilkins](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Wilkins,-Martin--tojpeg_1471534953361_x4.jpg)
Professor Martin Wilkins
Head of Department of Medicine
Professor Keith Willison
![Professor Keith Willison](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Willison,-Keith--tojpeg_1471535039414_x4.jpg)
Professor Keith Willison
Chair in Chemical Biology