Critical care wardCritical care involves the care of the sickest patients in the hospital. Critically ill patients have usually been through a significant insult to their body (such as trauma, infection, burn) and have developed organ failure and require life-support. Critical Care is the largest theme bringing together clinicians and scientists from diverse backgrounds and includes collaborative research from hospitals throughout north-west London. Investigations range from evaluating biological mechanisms of organ failure through to the development of innovative technologies which allow the short-term and long-term support and recovery of organs. 

Many people are exposed to the environment of an Intensive care unit (ICU) either personally or through a family member. It is often a life-changing event and our work aims to reduce this impact facilitating post-ICU recovery.

Research themes:


Citation

BibTex format

@article{Scott:2011:10.1074/jbc.M111.277434,
author = {Scott, AJ and O'Dea, KP and O'Callaghan, D and Williams, L and Dokpesi, JO and Tatton, L and Handy, JM and Hogg, PJ and Takata, M},
doi = {10.1074/jbc.M111.277434},
journal = {JOURNAL OF BIOLOGICAL CHEMISTRY},
pages = {35466--35476},
title = {Reactive Oxygen Species and p38 Mitogen-activated Protein Kinase Mediate Tumor Necrosis Factor alpha-Converting Enzyme (TACE/ADAM-17) Activation in Primary Human Monocytes},
url = {http://dx.doi.org/10.1074/jbc.M111.277434},
volume = {286},
year = {2011}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AU - Scott,AJ
AU - O'Dea,KP
AU - O'Callaghan,D
AU - Williams,L
AU - Dokpesi,JO
AU - Tatton,L
AU - Handy,JM
AU - Hogg,PJ
AU - Takata,M
DO - 10.1074/jbc.M111.277434
EP - 35476
PY - 2011///
SP - 35466
TI - Reactive Oxygen Species and p38 Mitogen-activated Protein Kinase Mediate Tumor Necrosis Factor alpha-Converting Enzyme (TACE/ADAM-17) Activation in Primary Human Monocytes
T2 - JOURNAL OF BIOLOGICAL CHEMISTRY
UR - http://dx.doi.org/10.1074/jbc.M111.277434
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295927100018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - http://hdl.handle.net/10044/1/19389
VL - 286
ER -