Cell and developmental biology
Members use a wide range of techniques (gene tagging, silencing, microarrays, RNA/ChIP-seq, -omics technologies) and imaging approaches (high-throughput microscopy to in vivo whole animal and single cell resolution), in addition to in silico structural modelling and mathematical modelling of gene families, molecular pathways, and complex cellular systems. The groups in this theme focus on the cellular and molecular mechanisms which regulate development, maintenance, repair and regeneration of tissues. We use a variety of experimental models, including mouse, zebrafish, C. elegans, Drosophila, Arabidopsis, Blumeria graminis, and a range of protozoan and metazoan pathogens.
Studies on individual cells/organisms are complemented by population studies in an effort to understand the evolutionary drivers of gene selection. Strong links with groups in Physics, Chemistry, Mathematics and Engineering support the development of novel, interdisciplinary approaches that take advantage of cutting-edge technological advances to address challenging biological questions.
Institutes, centres and initiatives
This Research Theme is associated to the following institutes, centres and initiatives:
- Antimicrobial Research Collaborative
- Centre for Advanced Therapeutics
- Department of Immunology and Inflammation
- Hic-Vac
- Institute of Infection
- Malaria Network
- Physics of Life Network
- Stem Cell Regenerative Medicine Network
- Vascular Science Network
- Wound Healing and Regeneration Network
Academic Staff in this area
Dr Michalis Barkoulas
Dr Michalis Barkoulas
Senior Lecturer
Professor Jake Baum
Professor Jake Baum
Visiting Professor
Dr Tolga Bozkurt
Dr Tolga Bozkurt
Senior Lecturer
Professor Hugh J M Brady
Professor Hugh J M Brady
Professor of Immunology
Dr Matthew A Child
Dr Matthew A Child
Research Fellow (Sir Henry Dale Fellow)
Dr Tiago Cunha Luis
Dr Tiago Cunha Luis
Sir Henry Dale Fellow
Professor Maggie Dallman OBE
Professor Maggie Dallman OBE
Vice-President (International), Associate Provost (Acad P)
Dr Marc S Dionne
Dr Marc S Dionne
Reader in Innate Immunity
Professor Robert G Endres
Professor Robert G Endres
Professor of Systems Biology
Professor Cristina Lo Celso
Professor Cristina Lo Celso
Co-Director Centre for Haematology & Prof Stem Cell Biology
Dr Ruben Perez-Carrasco
Dr Ruben Perez-Carrasco
Lecturer in Theoretical Systems Biology
Professor Gloria Rudenko
Professor Gloria Rudenko
Professor of Molecular Microbiology
Professor Murray Selkirk
Professor Murray Selkirk
Professor of Biochemical Parasitology
Dr Giovanni Sena
Dr Giovanni Sena
Senior Lecturer
Dr Jie Song
Dr Jie Song
Research Fellow (The Royal Society)
Dr Tony D Southall
Dr Tony D Southall
Senior Lecturer
Professor Colin G N Turnbull
Professor Colin G N Turnbull
Professor of Plant Sciences