Cell and developmental biology
The groups in this theme focus on the cellular and molecular mechanisms which regulate development, maintenance, repair and regeneration of tissues. We use a variety of experimental models, including mouse, zebrafish, C. elegans, Drosophila, Arabidopsis, Blumeria graminis, and a range of protozoan and metazoan pathogens. Members use a wide range of techniques (gene tagging, silencing, microarrays, RNA/ChIP-seq, -omics technologies) and imaging approaches (high-throughput microscopy to in vivo whole animal and single cell resolution), in addition to in silico structural modelling and mathematical modelling of gene families, molecular pathways, and complex cellular systems.
Studies on individual cells/organisms are complemented by population studies in an effort to understand the evolutionary drivers of gene selection. Strong links with groups in Physics, Chemistry, Mathematics and Engineering support the development of novel, interdisciplinary approaches that take advantage of cutting-edge technological advances to address challenging biological questions.
Research groups
Dr Michalis Barkoulas
Dr Michalis Barkoulas
Senior Lecturer
Professor Jake Baum
Professor Jake Baum
Professor of Cell Biology and Infectious Diseases
Dr Tolga Bozkurt
Dr Tolga Bozkurt
Senior Lecturer
Professor Hugh J M Brady
Professor Hugh J M Brady
Professor of Immunology
Dr Tiago Cunha Luis
Dr Tiago Cunha Luis
Sir Henry Dale Fellow
Professor Maggie Dallman
Professor Maggie Dallman
Vice-President (International), Associate Provost (Acad P)
Professor Robert G Endres
Professor Robert G Endres
Professor of Systems Biology
Dr Kleoniki Gounaris
Dr Kleoniki Gounaris
Senior Lecturer, Director of Postgraduate Studies
Dr Nadia Guerra
Dr Nadia Guerra
Senior Lecturer
Professor Armand M Leroi
Professor Armand M Leroi
Professor of Evolutionary Developmental Biology
Professor Cristina Lo Celso
Professor Cristina Lo Celso
Professor of Stem Cell Biology
Dr Kirsten McEwen
Dr Kirsten McEwen
Visiting Researcher
Professor Gloria Rudenko
Professor Gloria Rudenko
Professor of Molecular Microbiology
Professor Murray Selkirk
Professor Murray Selkirk
Professor of Biochemical Parasitology
Dr Giovanni Sena
Dr Giovanni Sena
Senior Lecturer
Emeritus Professor Robert E Sinden D.Sc. FMedSci
Emeritus Professor Robert E Sinden D.Sc. FMedSci
Emeritus Professor of Parasite Cell Biology
Dr Jie Song
Dr Jie Song
Research Fellow (The Royal Society)
Dr Tony D Southall
Dr Tony D Southall
Senior Lecturer
Professor Michael P H Stumpf
Professor Michael P H Stumpf
Visiting Professor
Professor Colin G N Turnbull
Professor Colin G N Turnbull
Professor of Plant Sciences
Dr Dina Vlachou
Dr Dina Vlachou
Research Fellow