@article{Scheelbeek:2016:10.1016/S2214-109X(16)30023-7,
author = {Scheelbeek, PFD and Chowdhury, MAH and Haines, A and Alam, A and Hoque, MA and Butler, AP and Khan, AE and Mojumder, SK and Blangiardo, MAG and Elliott, P and Vineis, P},
doi = {10.1016/S2214-109X(16)30023-7},
journal = {Lancet Global Health},
title = {High concentrations of sodium in drinking water and raised blood pressure in coastal deltas affected by episodic seawater inundations},
url = {http://dx.doi.org/10.1016/S2214-109X(16)30023-7},
volume = {4},
year = {2016}
}

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TY  - JOUR
AB  - Background In times of seawater inundation in coastal deltas, unprotected drinking water sources, such as ponds andshallow tube wells, take on salt water with each inundation. Daily consumption of these saline sources contributes tooverall sodium intake. Although there is evidence that a high dietary salt intake is an important risk factor forhypertension, little is known about the eff ect of high concentrations of sodium in drinking water on populationhealth. In this longitudinal study, we aimed to measure the eff ect of high concentrations of sodium in drinking wateron blood pressure and to assess the reversibility of raised blood pressure when conventional drinking water sourceswere replaced by low-saline water.Methods We used a multistage sampling process to recruit participants aged 18 years or older from the salinityaffectedsub-districts of Dacope, Batiagatha, and Paikgatchha in coastal Bangladesh. Most participants consumeddrinking water from highly saline sources, such as ponds and tube-wells, while a small percentage had access torainwater. In March, 2013, we recorded: baseline concentrations of sodium in drinking water; participants’ bloodpressure; and personal, lifestyle, and environmental characteristics. During the study period, some study participantsgained access to low-saline drinking water alternatives that were installed for use in the dry season, when water fromponds becomes more saline. In March, 2014, and May, 2014, we made follow-up assessments of drinking watersodium, blood pressure, and repeated the questionnaire about personal, lifestyle, and environmental characteristics.We used generalised linear mixed methods to model the eff ect of drinking water sodium on blood pressure andassess reversibility of raised blood pressure when participants switched from conventional drinking water sources tolow-saline alternatives.Findings We included data from 581 participants in analysis, of which 277 (48%) were male. Median age was 38 years(IQR 30&
AU  - Scheelbeek,PFD
AU  - Chowdhury,MAH
AU  - Haines,A
AU  - Alam,A
AU  - Hoque,MA
AU  - Butler,AP
AU  - Khan,AE
AU  - Mojumder,SK
AU  - Blangiardo,MAG
AU  - Elliott,P
AU  - Vineis,P
DO  - 10.1016/S2214-109X(16)30023-7
PY  - 2016///
SN  - 2214-109X
TI  - High concentrations of sodium in drinking water and raised blood pressure in coastal deltas affected by episodic seawater inundations
T2  - Lancet Global Health
UR  - http://dx.doi.org/10.1016/S2214-109X(16)30023-7
UR  - http://hdl.handle.net/10044/1/31356
VL  - 4
ER  - 

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