Respiratory syncytial virus (RSV), 3D illustration which shows two types of viral surface spikes

Respiratory Syncytial Virus (RSV) Human Challenge Study

OPEN FOR RECRUITMENT

We are looking for healthy volunteers aged 65 - 75 years old to take part in an RSV Challenge Study. 

The study involves a screening visit and an inpatient quarantine stay, during which participants will be deliberately given RSV (respiratory syncytial virus) and carefully monitored for 11 days.

This is followed by 3 follow-up visits over a 3-month period. 

 Some participants will also attend a baseline visit approximately 2 weeks before admission for a baseline bronchoscopy procedure.

Depending on the study group, participants may undergo up to 3 bronchoscopy procedures, which will be fully explained by the study team.  

If you are eligible and want to take part, you will be reimbursed up to £2,700 for your time and inconvenience, depending on the study group. 

Read the full information sheet here: CHIRP02_PIS_V2.0_18AUG2026

Imperial College London, in collaboration with Imperial College Healthcare NHS Trust, and funded by the European project “Inno4Vac” to conduct a human infection study (also known as a controlled human infection challenge study) with Respiratory Syncytial Virus (RSV).  


Upcoming Quarantines

Quarantine Number

Admission Date

Challenge Date

Discharge Date

Status

Quarantine 1

Monday 23rd November 2026

Tuesday 24th November 2026

Friday 4th December 2026

OPEN

N/A

Contact us

To get in touch with the study team, please email: imperial.humanchallenge@nhs.net  

Join our Research Registry!

The Chief Investigator of this study, Professor Chris Chiu, who works in the Department of Infectious Diseases at Imperial College London, has over 10 years of experience running vaccine and challenge studies for respiratory diseases such as Flu, RSV and COVID-19, in adults aged between 18-75years.  

 If this study isn’t for you, but you’d like to join our registry to be contacted about other studies we may be running, then please email us: flu-rsv-study@imperial.ac.uk