Imperial College London has international reputation for research in perinatal neurology and brain imaging, spanning over several decades. We lead one of the largest clinical research programs in neonatal encephalopathy in the world. Neonatal encephalopathy, or brain injury related to 'birth asphyxia' is a devastating condition due to a presumed lack of oxygen and blood flow to the fetal brain, possibly around the time of birth. Pioneering research undertaken in the unit, along with many other researchers and collaborators in the UK and worldwide led to the establishment of brain cooling as the first effective therapy for neonatal encephalopathy. However, despite cooling therapy, almost half of the babies born with neonatal encephalopathy will have adverse outcomes.
Our current work is focussed on developing effective disease stratification tools for developing personalised neuroprotection in neonatal encephalopathy and evaluating these using quantitative MR spectroscopy biomarkers in a multi-country setting.
HELIX trial results in Lancet Global Health
Research team
Dr Sudhin Thayyil
Dr Sudhin Thayyil
Professor of Perinatal Perinatal Neuroscience and Centre Director
Dr. Reema Garegrat
Dr. Reema Garegrat
Clinical Research Fellow in Neonatal Neurology
Ms Martin, Caroline J
Ms Martin, Caroline J
Trial Manager for COMET
Dr Paolo Montaldo
Dr Paolo Montaldo
MRC Doctoral Research Fellow
Dr Constance Burgod
Dr Constance Burgod
Postdoctoral researcher
Dr Vaisakh Krishnan
Dr Vaisakh Krishnan
Clinical Research Associate (PhD student)
Dr. Pallavi Muraleedharan
Dr. Pallavi Muraleedharan
NIHR SPARK Fellow and Research Associate (PhD Student)
Mr Mahesh Javarappa
Mr Mahesh Javarappa
Finance Manager
Ms Harini V
Ms Harini V
Data Manager
Contact us
Centre for Perinatal Neuroscience
Department of Brain Sciences
5th Floor, Hammersmith House
Hammersmith Hospital
Du Cane Road
London, W12 0HS
Ms Martin, Caroline J
Clinical Trials Manager, Centre for Perinatal Neuroscience
Room 515, Hammersmith House
+44 (0) 78 1753 2977
c.martin1@imperial.ac.uk