Pillar 1 • Telemetry Journal Article (2025)
Lead investigator: Prof Michael Fertleman
Letter to the editor-Brain Pro-TCT: a prospective, quasi-experimental study on early delirium detection with delirium observation screening scale vs. single-channel EEG after cardiac surgery in patients aged over 70 years
Haria, Chirag, Harris, Benjamin HL, Koizia, Louis J, Fertleman, Michael B
Show abstract
Abstract: This letter to the editor refers to ‘Brain Pro-TCT: a prospective, quasi-experimental study on early delirium detection with Delirium Observation Screening Scale vs. single-channel EEG after cardiac surgery in patients aged over 70 years’, by M. ten Broeke et al., https://doi.org/10.1093/eurjcn/zvaf
Pillar 1 • Telemetry Journal Article (2024)
Lead investigator: Prof Michael Fertleman
Fully automated and AI-assisted optical fiber sensing system for multiplexed and continuous brain monitoring
Zhang, Yuqian, Zhang, Naihan, Hu, Yubing, Pereira, Christopher, Fertleman, Michael, Jiang, Nan, Yetisen, Ali K
Show abstract
Abstract: Continuous and comprehensive brain monitoring is crucial for timely identification of changes or deterioration in brain function, enabling prompt intervention and personalized treatments. However, existing brain monitoring systems struggle to offer continuous and accurate monitoring of multiple brai
Pillar 1 • Telemetry Journal Article (2020)
Lead investigator: Prof Michael Fertleman
Protecting healthcare workers during the COVID-19 pandemic with new technologies: acceptability, feasibility and impact of the HoloLens2™ mixed reality headset across multiple clinical settings
Martin, Guy, Koiza, Louis, Kooner, Angad, Cafferkey, John, Ross, Clare, Purkayastha, Sanjay, Sivananthan, Arun, Tanna, Anisha, Pratt, Philip, Kinross, James
Show abstract
Abstract: Background: The COVID-19 pandemic has led to rapid acceleration in the deployment of new digital technologies to improve both accessibility and quality of care, and to protect staff. Mixed reality technology is the latest iteration of telemedicine innovation and is logical next step in the move tow
Pillar 1 • Telemetry Journal Article (2026)
Lead investigator: Prof Michael Fertleman
Towards continuous brain monitoring: a pilot qualitative study of user experiences with in-ear EEG
Haria, Chirag, Harris, Benjamin, Koizia, Louis, Fertleman, Michael
Show abstract
Abstract: In-ear electroencephalography (EEG) is an emerging form of wearable neurotechnology that offers the potential for continuous and unobtrusive brain monitoring outside traditional clinical settings. While technical feasibility has been demonstrated across applications including seizure detection, sle
Pillar 2 • Metabolomics Journal Article (2022)
Lead investigator: Prof Michael Fertleman
Cytokine changes in cerebrospinal fluid following vascular surgery on the thoracic aorta.
Pereira, Christopher, Perera, Anisha H, Rudarakanchana, Nung, Harris, Benjamin HL, Di Giovannantonio, Matteo, Taylor-Robinson, Simon D, Dani, Melanie, Fertleman, Michael
Show abstract
Abstract: There is growing evidence that surgery can drive an inflammatory response in the brain. However, the mechanisms behind this response are incompletely understood. Here, we investigate the hypotheses that 1. Cerebrospinal fluid (CSF) cytokines increase after vascular surgery and 2. That these changes
Pillar 2 • Metabolomics Journal Article (2022)
Lead investigator: Prof Michael Fertleman
Putative involvement of cytokine modulation in the development of peri-operative neurocognitive disorders
Pereira, Christopher, Dani, melanie, Taylor-Robinson, simon, Fertleman, michael
Show abstract
Abstract: Following surgery, local cytokine-driven inflammation occurs, as part of the normal healing process. Cytokines in the central nervous system such as IL-6 and IL-8 may also be elevated. These cytokine changes likely contribute to neuroinflammation, but the complex mechanisms through which this occurs
Pillar 2 • Metabolomics Journal Article (2022)
Lead investigator: Prof Michael Fertleman
Cytokine changes in cerebrospinal fluid and plasma post-emergency orthopaedic surgery
Fertleman, Michael, Pereira, Chris, Dani, Melanie, Harris, Benjamin, Di Giovannantonio, Matteo, Taylor-Robinson, Simon
Show abstract
Abstract: Neuroinflammation after surgery and its contribution to peri-operative neurocognitive disorders (PND) is not well understood. Studying the association between central and peripheral cytokines and neuroinflammation is a prelude to the development of treatments for PND. Here, we investigate the hypoth
Pillar 3 • Cardiology Journal Article (2026)
Lead investigator: Dr Louis John Koizia & Prof Michael Fertleman
Multidisciplinary team–guided management of severe aortic stenosis: five-year outcomes following TAVI versus conservative treatment
Manning, Jane, Koizia, Louis, Dani, Melanie, Malik, Iqbal, Di Giovannantonio, Matteo, Harris, Benjamin HL, Fertleman, Michael
Show abstract
Abstract: Objective: Multidisciplinary team (MDT) meetings are central to treatment decisions in aortic stenosis (AS), particularly for borderline or high-risk patients. This study evaluates long-term, real-world outcomes according to MDT selected management strategy within routine clinical practice in this
Pillar 3 • Cardiology Journal Article (2022)
Lead investigator: Dr Louis John Koizia & Prof Michael Fertleman
The associations of psoas and masseter muscles with sarcopenia and related adverse outcomes in older trauma patients: a retrospective study
Varma, Surabhi, Wilson, Michael SJ, Naik, Mitesh, Sandhu, Amandeep, Ota, Helen Chidera Uchenna, Aylwin, Christopher, Fertleman, Michael, Peck, George
Show abstract
Abstract: Background There is an emerging role for radiological evaluation of psoas muscle as a marker of sarcopenia in trauma patients. Older trauma patients are more likely to undergo cranial than abdomino-pelvic imaging. Identifying sarcopenia using masseter cross-sectional area (M-CSA) has shown correlati
Pillar 3 • Cardiology Journal Article (2022)
Lead investigator: Dr Louis John Koizia & Prof Michael Fertleman
Futility in transcatheter aortic valve implantation: a search for clarity
Patel, Kush P, Treibel, Thomas A, Scully, Paul R, Fertleman, Michael, Searle, Samuel, Davis, Daniel, Moon, James C, Mullen, Michael J
Show abstract
Abstract: Although transcatheter aortic valve implantation (TAVI) has revolutionised the landscape of treatment for aortic stenosis, there exists a cohort of patients where TAVI is deemed futile. Among the pivotal high-risk trials, one-third to half of patients either died or received no symptomatic benefit f
Pillar 3 • Cardiology Journal Article (2021)
Lead investigator: Dr Louis John Koizia & Prof Michael Fertleman
Takotsubo cardiomyopathy in elderly female trauma patients - a case series and mini-review
Patel, Vishal, Levy, Shuli, Malik, Iqbal, Fertleman, Michael, Koizia, Louis
Show abstract
Abstract: Takotsubo cardiomyopathy is a syndrome characterised by acute left ventricular wall motion abnormalities leading to left ventricular systolic dysfunction. It remains an important differential diagnosis for acute coronary syndrome. For patients requiring surgical management, delays in the diagnosis o
Pillar 3 • Cardiology Journal Article (2020)
Lead investigator: Dr Louis John Koizia & Prof Michael Fertleman
The utility of psoas muscle assessment in predicting frailty in patients undergoing transcatheter aortic valve replacement
Koizia, Louis, Naik, Mitesh, Peck, George, Mikhail, Ghada W, Sen, Sayan, Malik, Iqbal S, Ariff, Ben, Fertleman, Michael B
Show abstract
Abstract: Background. The rise in an ageing population has resulted in an increase in the prevalence of aortic stenosis. With the advent and rapid expansion in the use of transcatheter aortic valve replacements (TAVRs), patients with severe aortic stenosis, traditionally thought too high risk for surgical int
Pillar 4 • Biomechanics Journal Article (2025)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Weather and hip fractures: a nine-year study across England and Wales
Koizia, Louis, Jensen, Kjeld, Yearling, David, Barang, Gav, Harris, Benjamin, Fertleman, Michael
Show abstract
Abstract: Background: Hip fractures are a leading orthopaedic injury worldwide, often causing disability, cognitive decline, and loss of independence. Identifying early predictors is therefore a major healthcare priority yet the impact of weather on hip fracture incidence remains poorly understood. This study
Pillar 4 • Biomechanics Journal Article (2025)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Why we need a patient-centered innovation renaissance: a horizontal and vertical integration of knowledge to transform care pathways
Vandekerckhove, Pieter, Harris, Benjamin HL, Koizia, Louis J, Handa, Ashok, Brainard, Chris, Howard, Steven
Show abstract
Abstract: We are at a pivotal moment. The future of healthcare innovation can no longer be defined solely by technological advancement or institutional efficiency. While digital tools, therapies and platforms continue to evolve, they must be embedded within a broader transformation, one that places the human
Pillar 4 • Biomechanics Journal Article (2025)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Letter to editor
Koizia, Louis J, Allott, Vincent ES, Fertleman, Michael B, Harris, Benjamin HL
Pillar 4 • Biomechanics Journal Article (2025)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
“Factors affecting advance care planning in older adults with cancer” – avenues for future research
Allott, Vincent ES, Harris, Benjamin HL, Fertleman, Michael B, Koizia, Louis J
Pillar 4 • Biomechanics Journal Article (2025)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Genome-wide study of the UK Biobank highlights the importance of the homeobox-C gene cluster in hip fracture risk
Koizia, Louis, Giovannantonio, Matteo Di, Zhang, Ping, Fertleman, Michael Barry, Harris, Benjamin Howell Lole
Show abstract
Abstract: Introduction Hip fractures are among the most common major orthopaedic injuries globally, with one in three women and one in twelve men projected to sustain a hip fracture in their lifetime. Identifying genetic factors that contribute to hip fracture risk could improve risk stratification and inform
Pillar 4 • Biomechanics Journal Article (2023)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
In healthy volunteers the Miami-J® cervical collar causes swallow dysfunction. This may increase the risk of aspiration; of particular potential consequence in older people with neck injury
Hudson, MAJ, Ehsanullah, J, Lee, A, Macpherson, N, O'Gilvie, A, Shrestha, A, Tsang, K, Morgan, C, Peck, G, Koizia, LJ, Fertleman, MB
Show abstract
Abstract: Background: In young healthy volunteers a cervical hard collar has been shown to change swallowing physiology. The risk of aspiration pneumonia increases with age. Methods: In this open prospective dual-arm controlled trial without randomisation there were 23 patients divided into two cohorts: 11 ol
Pillar 4 • Biomechanics Journal Article (2023)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Hard to swallow: remembering to check for impacted dentures in elderly patients presenting with swallowing difficulty
Ramesh, Priyavarshini, Morgan, Cerys, Fertleman, Michael, John Koizia, Louis
Show abstract
Abstract: Background: Swallowing difficulty is a common issue associated with hospital admission and can be due to a variety of causes, including accidental ingestion of dentures. This case highlights the importance of ensuring aids such as dentures are accounted for early in elderly patients presenting with
Pillar 4 • Biomechanics Journal Article (2022)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Acute sarcopenia after elective and emergency surgery
Shrestha, Alvin, Dani, Melanie, Kemp, Paul, Fertleman, Michael
Show abstract
Abstract: Abstract Sarcopenia is an increasingly recognised condition of loss of muscle mass and function. The European Working Group on Sarcopenia in Older People 2 (EWSOP2) updated their definition in 2018, emphasising the importance of low muscle strength in diagnosis. Acute sarcopenia has been arbitrarily
Pillar 4 • Biomechanics Journal Article (2022)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Why do older adults stand-up differently to young adults?: investigation of compensatory movement strategies in sit-to-walk
van der Kruk, Eline, Strutton, Paul, Koizia, Louis J, Fertleman, Michael, Reilly, Peter, Bull, Anthony MJ
Show abstract
Abstract: Functional motor redundancy enables humans to move with distinct muscle activation patterns while achieving a similar outcome. Since humans select similar strategies, there seems to be an optimal control. However, older adults move differently to young adults. The question is whether this is this du
Pillar 4 • Biomechanics Journal Article (2022)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Consent for orthopaedic trauma surgery during the COVID-19 pandemic
Selmi, Hussain, Davies, Andrew, Walker, Joseph, Heaton, Toby, Sabharwal, Sanjeeve, Dani, Melanie, Fertleman, Michael, Reilly, Peter
Show abstract
Abstract: INTRODUCTION: The COVID-19 pandemic has brought a series of new challenges to the management of surgical patients. The consent process relies on a foundation of open and non-coerced discussion between clinician and patient, which includes all the potential risks of surgery. This must be updated to i
Pillar 4 • Biomechanics Journal Article (2022)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
We must consider a growing opioid epidemic in older people
Hudson, murray, Koizia, Louis, Fertleman, Michael
Pillar 4 • Biomechanics Journal Article (2022)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Weight loss surgery in the elderly: is this the future
Hillier, Marston, Dani, melanie, Fertleman, michael, Purkayastha, sanjay, Koizia, Louis
Show abstract
Abstract: The UK population is ageing rapidly, and the proportion of people living with obesity is increasing. Obesity is a risk factor for diabetes, coronary artery disease, stroke and cancer. Older patients are admitted for obesity related complications at a similar rate compared to younger patients. Howeve
Pillar 4 • Biomechanics Journal Article (2022)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Uterine transplantation: Legal and regulatory implications in England
Vali, Saaliha, Jones, Benjamin P, Saso, Srdjan, Fertleman, Michael, Testa, Giuliano, Johanesson, Liza, Alghrani, Amel, Smith, Richard
Show abstract
Abstract: Uterus transplantation (UTx) is fast evolving from an experimental to a clinical procedure, combining solid organ transplantation with assisted reproductive technology. The commencement of the first human uterus transplant trial in the United Kingdom leads us to examine and reflect upon the legal an
Pillar 4 • Biomechanics Journal Article (2022)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Describing the epidemiology of COVID-19 in Nigeria: an analysis of the first year of the pandemic
Oleribe, Obinna, Olawepo, Olatayo, Ezechi, Oliver, Osita-Oleribe, Princess, Fertleman, Michael, Taylor-Robinson, Simon
Show abstract
Abstract: We report the COVID-19 experience across Nigeria from March 2020 to March 2021. Demographics were obtained from Nigerian Center for Disease Control. By 21 March 2021, 161,737 people were confirmed positive for SARS-COV-2. Overall, testing rates were 0.8% of the population, with positivity rates of 9
Pillar 4 • Biomechanics Journal Article (2022)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Perioperative anticoagulation for colorectal cancer patients
Malani, Sangam, Bhattacharyya, Adrija, Souvatzi, Maria, Koizia, Louis
Show abstract
Abstract: Population ageing has substantially contributed to the rising number of new cancer cases worldwide. Fifty percent of new diagnoses of colorectal cancer are made in patients aged over 70 years, and 25% are aged 80 years or over. Older patients present with more co-morbidities and frailty than younger
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Perceptions and opinions of Nigerians to the management and response to COVID-19 in Nigeria.
Oleribe, Obinna Ositadimma, Idigbe, Ifeoma Eugenia, Osita-Oleribe, Princess, Olawepo, Olatayo, Musa, Zaidat Adesola, Aikhuomogbe, Samuel, Ezechi, Oliver Chukwujekwu, Fertleman, Michael, Salako, Babatunde, Taylor-Robinson, Simon David
Show abstract
Abstract: Introduction: we present a qualitative analysis of opinions of the Nigerian general public as to how successful healthcare strategies have been in containing the COVID-19 outbreak. Methods: an online qualitative survey was conducted, consisting of 30 semi-structured questions. Results: four hundred
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
A remote access mixed reality teaching ward round
Bala, Laksha, Kinross, James, Martin, Guy, Koizia, Louis J, Kooner, Angad S, Shimshon, Gideon J, Hurkxkens, Thomas J, Pratt, Philip J, Sam, Amir H
Show abstract
Abstract: Background Heterogeneous access to clinical learning opportunities and inconsistency in teaching is a common source of dissatisfaction among medical students. This was exacerbated during the COVID‐19 pandemic, with limited exposure to patients for clinical teaching. Methods We conducted a proof‐of‐
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Impact of COVID-19 second wave on healthcare worker staffing levels
Abuown, Ala, Taube, Catharine, Koizia, Louis J
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
The influence of cervical spine angulation on symptoms associated with wearing a rigid neck collar
Kelani, Taiwo, Lee, Annabelle, Walker, Miny, Koizia, Louis, Dani, Melanie, Fertleman, Michael, Kedgley, Angela
Show abstract
Abstract: Introduction: Rigid cervical spine collars can be used to maintain the position of the cervical spine following injury or surgery. However, they have been associated with difficulty swallowing, pressure sores and pain, particularly in older patients. We aimed to investigate the relationship between
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity
Rosa, Annachiara, Pye, Valerie E, Graham, Carl, Muir, Luke, Seow, Jeffrey, Ng, Kevin W, Cook, Nicola J, Rees-Spear, Chloe, Parker, Eleanor, dos Santos, Mariana Silva, Rosadas, Carolina, Susana, Alberto, Rhys, Hefin, Nans, Andrea, Masino, Laura, Roustan, Chloe, Christodoulou, Evangelos, Ulferts, Rachel, Wrobel, Antoni G, Short, Charlotte-Eve, Fertleman, Michael, Sanders, Rogier W, Heaney, Judith, Spyer, Moira, Kjaer, Svend, Riddell, Andy, Malim, Michael H, Beale, Rupert, MacRae, James, Taylor, Graham P, Nastouli, Eleni, van Gils, Marit J, Rosenthal, Peter B, Pizzato, Massimo, McClure, Myra O, Tedder, Richard S, Kassiotis, George, McCoy, Laura E, Doores, Katie J, Cherepanov, Peter
Show abstract
Abstract: The coronaviral spike is the dominant viral antigen and the target of neutralizing antibodies. We show that SARS-CoV-2 spike binds biliverdin and bilirubin, the tetrapyrrole products of heme metabolism, with nanomolar affinity. Using cryo–electron microscopy and x-ray crystallography, we mapped the
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Antibody response to SARS-CoV-2 infection is not associated with Post-COVID-19 Syndrome in healthcare workers
Pereira, Christopher, Harris, Benjamin, Di Giovannantonio, Matteo, Rosadas, Carolina, Short, Charlotte-Eve, Quinlan, Rachael, Sureda-Vives, Macià, Fernandez, Natalia, Day-Weber, Isaac, Khan, Maryam, Marchesin, Federica, Katsanovskaja, Ksenia, Parker, Eleanor, Taylor, Graham, Tedder, Richard, McClure, Myra, Dani, Melanie, Fertleman, Michael
Show abstract
Abstract: It is currently unknown how Post-COVID-19 Syndrome (PCS) may affect those infected with SARS-CoV-2. This longitudinal study reports on healthcare staff who tested positive for SARS-CoV-2 between March-April 2020 and follows their antibody titres and symptomatology. Over half (n=21/38) had PCS at 7-8
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
An unusual cause of gastrointestinal perforation in an adolescent patient with beta-thalassemia on deferasirox and SARS-CoV-2 infection
Chauhan, Devkishan, Kilic, Yakup, Segal, Jonathan P, Patel, Neil, Koizia, Louis
Show abstract
Abstract: Chelation therapy is recognized as a safe and effective treatment option in patients with beta-thalassemia with iron overload. We report an 18-year-old male with acute abdomen and gastrointestinal bleeding with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection secondary to gastr
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Does the weather contribute to admissions of neck of femur fractures?
Koizia, Louis, Dani, Melanie, Brown, Hannah, Lee, Malcolm, Reilly, Peter, Fertleman, Michael
Show abstract
Abstract: Background: The effects of weather on overall mortality are well documented. Anecdotally, icy conditions are perceived to result in more falls and admissions for neck of femur (NOF) fractures. The aim of this pilot study was to determine whether relationships could be extracted or at least not ruled
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Face coverings Mask Effective Communication
Chauhan, aneesha, Morgan, cerys, Fertleman, Michael, Koizia, Louis
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in a rehabilitation facility: evolution of the presence of nasopharyngeal SARS-CoV-2 and serological antibody responses.
Harris, Benjamin HL, Zuhair, Mohamed, Di Giovannantonio, Matteo, Rosadas, Carolina, Khan, Maryam, Short, Charlotte-Eve, Thaventhiran, Thilipan, Quinlan, Rachael, Taylor, Andrew, Calvez, Ronan, Taylor, Graham P, Tedder, Richard S, McClure, Myra O, Fertleman, Michael
Show abstract
Abstract: At the start of the UK coronavirus disease 2019 epidemic, this rare point prevalence study revealed that one-third of patients (15 of 45) in a London inpatient rehabilitation unit were found to be infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) but asymptomatic. We report
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Asymptomatic COVID-19 in a rehabilitation facility: evolution of the presence of nasopharyngeal SARS-CoV-2 and serological antibody responses
Harris, Benjamin HL, Zuhair, Mohamed, di Giovannantonio, Matteo, Rosadas, Carolina, Short, Charlotte-Eve, Thaventhiran, Thilipan, Quinlan, Rachael, Taylor, Andy, Calvez, Ronan, Taylor, Graham P, Tedder, Richard S, McClure, Myra O, Fertleman, Michael
Show abstract
Abstract: At the start of the UK COVID-19 epidemic, this rare point prevalence study reveals ⅓ of patients in a London inpatient rehabilitation unit were found to be infected with SARS-CoV 2, but asymptomatic (n=15/45). We report on eight patients in detail, including their clinical stability, the evolution o
Pillar 4 • Biomechanics Journal Article (2021)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
The difficulty of managing recurrent sigmoid volvulus in a frail patient
Radia, Utsav, Malietzis, George, Dani, Melanie, Fertleman, Michael, Koizia, Louis
Show abstract
Abstract: Abdominal pain is a common cause for presentation of the older patient to healthcare services. Sigmoid volvulus is one of the leading causes of acute large bowel obstruction in adults. It affects older, comorbid, frailer and institutionalized patients. In this report, we highlight some of the clini
Pillar 4 • Biomechanics Journal Article (2020)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Clinical characteristics and predictors of mortality in patients with COVID-19 infection outside intensive care
Moledina, Saadiq, Maini, Alexander, Gargan, Alice, Harland, William, Jenney, Heloise, Phillips, Georgina, Thomas, Kate, Chauhan, Dev, Fertleman, Michael
Show abstract
Abstract: Background/introduction The Coronavirus Disease 2019 (COVID-19) pandemic has affected all aspects of inpatient hospital medicine with patients admitted from Level 1 (general medical wards) through to Level 3 (intensive care). Often, there are subtle physiological differences in these cohorts of pati
Pillar 4 • Biomechanics Journal Article (2020)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Public perception of COVID-19 management and response in Nigeria: a cross-sectional survey
Oleribe, Obinna, Ezechi, Oliver, Osita-Oliberi, Princess, Olawepo, Olatayo, Zaidat, Musa, Omolabi, Anddy, Fertleman, Michael, Salako, Babatunde, Taylor-Robinson, Simon
Show abstract
Abstract: Objectives: A study designed to assess the public perception of the response of government and its institutions to the COVID-19 pandemic in Nigeria. Setting: Self-selecting participants throughout Nigeria completed a self-administered questionnaire through an online cross-sectional survey. Partici
Pillar 4 • Biomechanics Journal Article (2020)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
COVID-19 Experience: Taking the right steps at the right time to prevent avoidable morbidity and mortality in Nigeria and other nations of the world
Oleribe, Obinna, Osita-Oleribe, Princess, Salako, Babatunde, Ishola, Temitope, Fertleman, Michael, Taylor-Robinson, Simon
Show abstract
Abstract: The 2020 Coronavirus pandemic has caused countless governmental and societal challenges around the world. Nigeria, Africa’s most populous nation, has been exposed in recent years to a series of epidemics including Ebola and Lassa Fever. In this paper we document our perception of the national respon
Pillar 4 • Biomechanics Journal Article (2020)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Cholecystectomy for complicated gallbladder and common biliary duct stones: current surgical management
Argiriov, Yanna, Dani, Melanie, Tsironis, Christos, Koizia, Louis J
Show abstract
Abstract: Gallstone disease accounts for the vast majority of acute surgical admissions in the UK, with a major treatment being cholecystectomy. Practice varies significantly as to whether surgery is performed during the acute symptomatic phase, or after a period of recovery. Differences in practice relate to
Pillar 4 • Biomechanics Journal Article (2020)
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Novel conservative approach to high surgical risk frail proximal femur Fractures.
Koizia, Alexander, Abuown, Ala, Vowles, Julie, Smith, Damien, Koizia, Louis J
Show abstract
Abstract: One of the major impacts following a neck of femur fracture is pain. Most patients (nearly all) undergo an operation. This usually includes the frailest terminal patients and deemed a palliative procedure to reduce ongoing pain. The operation comes with risks and can reduce life expectancy in these
Pillar 4 • Biomechanics Journal Article ()
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Nasogastric tube feeding in older patients: a review of current practice and challenges faced
Chauhan, Devkishan, Varma, Surabhi, Dani, Melanie, Fertleman, Michael, Koizia, Louis
Show abstract
Abstract: Nasogastric tube feeding is an essential way of delivering enteral nutrition when the oral route is insufficient or unsafe. Malnutrition is recognised as a reversible factor for sarcopenia and frailty. It is therefore crucial that malnutrition is treated in older inpatients who have dysphagia and re
Pillar 4 • Biomechanics Journal Article ()
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Retrospective analysis on mortality and morbidity in sigmoid volvulus
Rosenberg, Boris, Basra, Pavun, Hudson, Murray, Koizia, Louis
Show abstract
Abstract: Purpose: Sigmoid volvulus usually occurs in frailer patients with comorbidities, and can be associated with recurrence. Our exploratory study assesses long-term outcomes in this cohort. Methods: We retrospectively reviewed records of patients admitted with sigmoid volvulus to two inner-city acute
Pillar 4 • Biomechanics Journal Article ()
Lead investigator: Dr Louis John Koizia, Prof Benjamin Harris & Prof Michael Fertleman
Older adults’ perspectives on big data use in hip fracture research: a qualitative study
Koizia, Louis
Show abstract
Abstract: Background: Big data approaches are increasingly applied to hip fracture research, linking clinical, imaging, environmental and genomic data. Yet the views of older adults, whose data underpin these efforts, remain under-explored. Methods: Focused, semi-structured interviews were conducted with old
